758692-47-6

Basic information

• Product Name: Ethyl 2-(4-bromophenyl)-2-diazoacetate
• Synonyms: ETHYL 2-(4-BROMOPHENYL)-2-DIAZOACETATE;4-Bromo-alpha-diazobenzeneacetic acid ethyl ester
• CAS NO: 758692-47-6
• Molecular Formula: C₁₀H₉BrN₂O₂
• Molecular Weight: 269.09
• Mol File: 758692-47-6.mol

Chemical Properties

• Melting Point: 54 °C
• Appearance: /
• CAS DataBase Reference: Ethyl 2-(4-bromophenyl)-2-diazoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-(4-bromophenyl)-2-diazoacetate(758692-47-6)
• EPA Substance Registry System: Ethyl 2-(4-bromophenyl)-2-diazoacetate(758692-47-6)

Safety Data

• Hazardous Substances Data: 758692-47-6(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Ethyl 2-(4-bromophenyl)-2-diazoacetate is used as a reagent for diazo transfer reactions in organic synthesis. It generates carbenes, which are highly reactive intermediates essential for forming new carbon-carbon and carbon-heteroatom bonds, enabling the creation of a wide range of chemical compounds.
Used in Aromatic Ring Functionalization:
The 4-bromophenyl group in Ethyl 2-(4-bromophenyl)-2-diazoacetate makes it useful for the functionalization of aromatic rings. This property allows for the modification and introduction of various functional groups onto aromatic compounds, expanding the scope of chemical transformations and applications in different industries.
Used in Chemical Research:
Ethyl 2-(4-bromophenyl)-2-diazoacetate is employed in chemical research for studying the reactivity and properties of diazo compounds and carbenes. Its unique structure and reactivity provide valuable insights into the development of new synthetic methods and understanding the underlying mechanisms of various chemical reactions.
Used in Pharmaceutical Industry:
Ethyl 2-(4-bromophenyl)-2-diazoacetate is used as a building block or intermediate in the synthesis of pharmaceutical compounds. Its ability to generate carbenes and functionalize aromatic rings makes it a valuable tool in the development of novel drug molecules with potential therapeutic applications.
Used in Material Science:
In the field of material science, Ethyl 2-(4-bromophenyl)-2-diazoacetate is utilized for the synthesis of advanced materials with specific properties. Its reactivity and versatility in forming carbon-carbon and carbon-heteroatom bonds contribute to the development of new polymers, coatings, and other materials with unique characteristics for various applications.

InChI:InChI=1/C10H9BrN2O2/c1-2-15-10(14)9(13-12)7-3-5-8(11)6-4-7/h3-6H,2H2,1H3

Upstream product

• 14062-25-0 Ethyl 4-bromophenylacetate 
• 623-73-4 diazoacetic acid ethyl ester 
• 589-87-7 1,4-bromoiodobenzene 
• 2158-14-7 4-acetamidobenzenesulfonyl azide 
• 2009-97-4 ethyl 2-diazo-3-oxobutanoate 
• 108-86-1 bromobenzene 
• 37859-24-8 2-(4-bromophenyl)acetyl chloride 
• 1878-68-8 2-(4-bromophenyl)-acetic acid 
• 20201-26-7 ethyl 4-bromophenylglyoxylate 

Downstream Products

• 1398180-76-1 ethyl 2-(4-bromophenyl)-3,3,3-trifluoropropanoate 
• 1446051-17-7 ethyl 2-(4-bromophenyl)-2-(1-methyl-1H-indol-3-yl)acetate 
• 1609003-55-5 ethyl 2-(4-bromophenyl)-2-(4-hydroxyphenyl)acetate 
• 1609003-83-9 ethyl 2-(4-bromophenyl)-2-(2-hydroxy-5-methylphenyl)acetate 
• 1609003-85-1 3-(4-bromophenyl)-5-methylbenzofuran-2(3H)-one 

Relevant articles and documents

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Synthesis of Rhodium Complexes with Chiral Diene Ligands via Diastereoselective Coordination and Their Application in the Asymmetric Insertion of Diazo Compounds into E?H Bonds

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Copper-Catalyzed Oxidation of Hydrazones to Diazo Compounds Using Oxygen as the Terminal Oxidant

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