Betamethasone 21-Propionate, also known as Clobetasol Propionate EP Impurity K, is a degradation product of Betamethasone. It is a glucocorticoid with chemical properties of a white solid. BETAMETHASONE 21-PROPIONATE is known for its anti-inflammatory and immunosuppressive properties, making it a valuable pharmaceutical agent.

75883-07-7

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Basic information
1. Product Name: BETAMETHASONE 21-PROPIONATE
2. Synonyms: BETAMETHASONE 21-PROPIONATE;(11β,16β)-9-Fluoro-11,17-dihydroxy-16-Methyl-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
3. CAS NO:75883-07-7
4. Molecular Formula: C25H33FO6
5. Molecular Weight: 448.5243232
6. EINECS: N/A
7. Product Categories: Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
8. Mol File: 75883-07-7.mol
Chemical Properties
1. Melting Point: 223-226?C
2. Boiling Point: 588.715°C at 760 mmHg
3. Flash Point: 309.844°C
4. Appearance: /
5. Density: 1.281g/cm³
6. Vapor Pressure: 0mmHg at 25°C
7. Refractive Index: 1.567
8. Storage Temp.: Refrigerator
9. Solubility: Chloroform (Slightly), DMSO (Sparingly), Methanol (Slightly)
10. PKA: 11.97±0.70(Predicted)
11. CAS DataBase Reference: BETAMETHASONE 21-PROPIONATE(CAS DataBase Reference)
12. NIST Chemistry Reference: BETAMETHASONE 21-PROPIONATE(75883-07-7)
13. EPA Substance Registry System: BETAMETHASONE 21-PROPIONATE(75883-07-7)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 75883-07-7(Hazardous Substances Data)

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75883-07-7 Usage

Uses

Used in Pharmaceutical Industry:
Betamethasone 21-Propionate is used as a pharmaceutical agent for its potent anti-inflammatory and immunosuppressive effects. It is particularly effective in treating various skin conditions, such as eczema, psoriasis, and dermatitis, by reducing inflammation and suppressing the immune response.
Used in Veterinary Medicine:
In the veterinary medicine industry, Betamethasone 21-Propionate is used as a therapeutic agent for managing inflammation and immune-mediated conditions in animals. It can be applied topically or administered systemically, depending on the specific condition being treated.
Used in Research and Development:
Betamethasone 21-Propionate is also utilized in research and development for studying the effects of glucocorticoids on various biological processes. It serves as a valuable tool in understanding the mechanisms of inflammation, immune regulation, and the potential side effects of glucocorticoid therapy.

Check Digit Verification of cas no

The CAS Registry Mumber 75883-07-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,8,8 and 3 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 75883-07:
(7*7)+(6*5)+(5*8)+(4*8)+(3*3)+(2*0)+(1*7)=167
167 % 10 = 7
So 75883-07-7 is a valid CAS Registry Number.

InChI:InChI=1/C25H33FO6/c1-5-21(30)32-13-20(29)25(31)14(2)10-18-17-7-6-15-11-16(27)8-9-22(15,3)24(17,26)19(28)12-23(18,25)4/h8-9,11,14,17-19,28,31H,5-7,10,12-13H2,1-4H3/t14-,17-,18?,19-,22-,23-,24?,25?/m0/s1

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