75892-84-1Relevant academic research and scientific papers
Copper-catalyzed asymmetric silyl addition to alkenyl-substituted N -heteroarenes
Zeng, Ya-Li,Chen, Bo,Wang, Ya-Ting,He, Cheng-Yu,Mu, Zi-Yuan,Du, Ji-Yuan,He, Long,Chu, Wen-Dao,Liu, Quan-Zhong
, p. 1693 - 1696 (2020)
Asymmetric conjugate addition of PhMe2SiBPin to a wide range of N-heteroaryl alkenes proceeded in the presence of a copper catalyst coordinated with an easily accessible chiral phosphoramidite ligand to afford useful β-silyl N-heteroarenes in high yields (up to 96%) and excellent enantioselectivities (up to 97% ee).
