759-21-7 Usage
Uses
Used in Pharmaceutical Industry:
2-Cyano-3-methylbut-2-enoic acid is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the formation of complex organic molecules that are integral to the development of new drugs.
Used in Dye Industry:
In the dye industry, 2-Cyano-3-methylbut-2-enoic acid is used as a chemical intermediate for the production of dyes, where its reactivity allows for the creation of a wide range of color compounds.
Used in Pesticide Production:
2-Cyano-3-methylbut-2-enoic acid is used as a precursor in the manufacturing of pesticides, leveraging its reactivity to form compounds that can effectively control pests in agricultural settings.
Used in Plasticizer Production:
2-Cyano-3-methylbut-2-enoic acid is also used as an intermediate in the production of plasticizers, which are additives that increase the flexibility and workability of plastics.
Used in Rubber Chemicals:
2-Cyano-3-methylbut-2-enoic acid is utilized in the synthesis of rubber chemicals, contributing to the development of rubber products with enhanced properties.
Given the compound's reactivity and potential hazards, it is essential to handle and store 2-Cyano-3-methylbut-2-enoic acid with the utmost care to prevent accidents and ensure safety in all applications across various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 759-21-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,5 and 9 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 759-21:
(5*7)+(4*5)+(3*9)+(2*2)+(1*1)=87
87 % 10 = 7
So 759-21-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H7NO2/c1-4(2)5(3-7)6(8)9/h1-2H3,(H,8,9)
759-21-7Relevant academic research and scientific papers
FGFR4 Inhibitor. Compositions and their use in pharmaceutical preparations
-
Paragraph 0081-0084, (2021/10/27)
The invention provides 3 inhibitor which takes 4 - 4 dihydropyrimidine [5 - d,2] pyrimidine - (1H) FGFR4 ketone as a mother nucleus and has a covalent structure. The examples give 9 specific compounds and kinase inhibitory activity testing of these 9 compounds, wherein LX08 for FGFR4 kinase inhibitory activity is only 7 nm, lower than FIIN - 2 of the active control, and potential application prospects. In addition, by subjecting the synthesized compound to MALDI-TOF mass spectrometry, we found that compounds of LX01, LX05, LX06, LX07, LX08 are covalently bound to FGFR4 of Cys552, cannot covalently bind FGFR4 of Cys477, and LX09 are FGFR4 inhibitors which can be covalently bound to the two cysteines Cys552 and Cys477 in FGFR4.
CO2 absorbing cost-effective ionic liquid for synthesis of commercially important alpha cyanoacrylic acids: A safe process for activation of cyanoacetic acid
Sharma, Yogesh O.,Degani, Mariam S.
experimental part, p. 526 - 530 (2010/04/23)
Cost-effective and carbon dioxide absorbing ionic liquid, tri-(2-hydroxyethyl) ammonium acetate, was shown to perform multiple roles in Knoevenagel condensation. It acted as an environmentally benign solvent, as an activating catalyst for the less reactive cyanoacetic acid and also as a risk reduction medium for the unevenly generated large amount of CO2 gas for large scale reactions. The reaction was scaled up for multi-gram synthesis of commercially important alpha cyanoacrylic acids.
