75933-88-9Relevant academic research and scientific papers
(8-Quinolinesulfonyl)tetrazole: A New Type of Highly Efficient Coupling Agent for the Synthesis of Ribooligonucleotides by the Phosphortriester Approach
Takaku, Hiroshi,Yoshida, Masatoshi
, p. 589 - 593 (2007/10/02)
(8-Quinolinesulfonyl)Tetrazole (QS-tet) has been developed as a new type of highly efficient coupling agent in the synthesis of phosphotriester bonds.This reagent very rapidly completes the coupling reactions, and the yield is considerably higher than tha
4-CHLOROPHENYL 5-CHLORO-8-QUINOLYL PHOSPHOROTETRAZOLIDE: A HIGHLY EFFICIENT PHOSPHORYLATING AGENT FOR OLIGORIBONUCLEOTIDE SYNTHESIS
Takaku, Hiroshi,Nomoto, Tadaaki,Kamaike, Kazuo
, p. 543 - 546 (2007/10/02)
4-Chlorophenyl 5-chloro-8-quinolyl phosphorotetrazolide (2) was a highly efficient phosphorylating agent for the synthesis of 5'-O-dimethoxytrityl-2'-O-tetrahydropyranylnucleoside 3'-(4-chlorophenyl, 5-chloro-8-quinolyl) phosphates (4).The fully protected
