75937-26-7

Upstream product

• 17996-12-2 N-benzyloxycarbonyl-6-amino-1-hexanol 
• 124-63-0 methanesulfonyl chloride 
• 4048-33-3 6-amino-1-hexanol 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 142038-98-0 [6-(2-Amino-ethylamino)-hexyl]-carbamic acid benzyl ester 
• 74472-27-8 1-(Benzyloxycarbonyl)hexahydro-1H-azepine 
• 142039-00-7 N,N'-bis(tert-butoxycarbonyl)-N-<6-<(benzyloxycarbonyl)amino>hexyl>ethane-1,2-diamine 
• 1320338-50-8 {6-[4-(3-hexyl-ureido)-2-oxo-2H-pyrimidin-1-yl]-hexyl}-carbamic acid benzyl ester 
• 1320338-48-4 [6-(4-amino-2-oxo-2H-pyrimidin-1-yl)-hexyl]-carbamic acid benzyl ester 

Relevant academic research and scientific papers

DNA-directed alkylating agents. 5. Acridinecarboxamide derivatives of (1,2-diaminoethane)dichloroplatinum(II)

A series of acridine-2- and -4-carboxamide-linked analogues of PtenCl2 has been prepared and evaluated for biological activity against several tumor cell lines in vitro and in vivo. The platinum complexes were generally more cytotoxic than the

Ligand analog-irreversible enzyme inhibitor conjugates

The present invention encompasses a method for determining ligands in test samples comprising intermixing with the test sample a ligand analog-irreversible enzyme inhibitor conjugate and a binding protein bindable to the ligand and the ligand analog-irreversible enzyme inhibitor conjugate and wherein the amount of ligand analog-irreversible enzyme inhibitor conjugate bound by the binding protein is related to the amount of ligand in the test sample, said binding protein inactivating the irreversible enzyme inhibitor when bound to the ligand analog portion of the conjugate; intermixing an enzyme which is irreversibly inhibited by the ligand analog-irreversible enzyme inhibitor conjugate unbound by the binding protein; and intermixing substrate to the enzyme and monitoring the enzyme substrate reaction. The invention also includes ligand analog-irreversible enzyme inhibitor conjugates useful as reagents in practicing the method. Methods and reagents of the present are particularly useful in determining drugs, hormones, and the like in biological fluids.