75938-11-3

Upstream product

• 40173-90-8 3,4-dimethoxyphenethyl bromide 
• 21763-07-5 6,7-Dimethoxy-1,4-dihydro-2H-isoquinoline-3-one 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 4230-93-7 1,2-dimethoxy-4-(2-nitro-vinyl)-benzene 
• 16135-41-4 6,7-dimethoxy-3,4-dihydro-1H-2-benzopyran-3-one 
• 73053-80-2 ethyl 2-(bromomethyl)-4,5-dimethoxyphenylacetate 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 

Downstream Products

• 18065-77-5 N-(3,4-dimethoxy-β-phenethyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 523-02-4 2,3,10,11-tetramethoxy-5,6,7,8,13,13a-hexahydroisoquinolino[3,2-a]isoquinoline 

Relevant academic research and scientific papers

SYNTHESIS OF HETEROCYCLES VIA LACTONES A NEW ROUTE FOR THE SYNTHESIS OF N-β-PHENETHYLTETRAHYDROISOQUINOLINE ALKALOIDS

A convenient synthesis of N-β-phenethyl-1,2,3,4-tetrahydroisoquinoline alkaloids is described.Condensation of the bromo esters I a-b with β-phenethylamines II a-c afforded the N-β-phenethyl-3-isoquinolones III a-c.Lithium aluminium hydride reduction of th

Synthesis of Heterocycles via Lactones: Part VI Condensation of Bromo Esters with β-Phenethylamines, a New Route to Berbines: Synthesis of (+/-)-Xylopinine, (+/-)-Scoulerine, Isocoptisine and Pseudoepitetrahydroberberine

A new route involving the generation of a tricyclic lactam intermediate in one-step has been developed for the synthesis of 2,3,10,11-tetraoxygenated berbine alkaloids.Three such alkaloids have been synthesized besides scoulerine which is 2,9-dihydroxy-3,10-dimethoxyberbine (11).