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759417-05-5

monacolin K (hydroxy acid form) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 759417-05-5 Structure

  • Basic information

    1. Product Name: monacolin K (hydroxy acid form)
    2. Synonyms:
    3. CAS NO:759417-05-5
    4. Molecular Formula:
    5. Molecular Weight: 422.562
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 759417-05-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: monacolin K (hydroxy acid form)(CAS DataBase Reference)
    10. NIST Chemistry Reference: monacolin K (hydroxy acid form)(759417-05-5)
    11. EPA Substance Registry System: monacolin K (hydroxy acid form)(759417-05-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 759417-05-5(Hazardous Substances Data)

759417-05-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 759417-05-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,5,9,4,1 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 759417-05:
(8*7)+(7*5)+(6*9)+(5*4)+(4*1)+(3*7)+(2*0)+(1*5)=195
195 % 10 = 5
So 759417-05-5 is a valid CAS Registry Number.

759417-05-5Downstream Products

759417-05-5Relevant articles and documents

3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Inhibitors. 4. Side Chain Ester Derivatives of Mevinolin

Hoffman, W. F.,Alberts, A. W.,Anderson, P. S.,Chen, J. S.,Smith, R. L.,Willard, A. K.

, p. 849 - 852 (1986)

Modification of the 2(S)-methylbutyryl moiety of mevinolin led to a series of side chain ester derivatives.A systematic exploration of the structure-activity relationships showed that the introduction of an additional aliphatic group on the carbon α to the carbonyl group increased potency.This obsrevation led to the synthesis of compound 16, which has about 2.5 times the intrinsic inhibitory activity of mevinolin.

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