759427-20-8

Upstream product

• 153556-42-4 4-bromo-3-fluorobenzoic acid 

Downstream Products

• 1163248-72-3 2-(4-bromo-3-fluorophenyl)-5-ethyloxazole 
• 1269647-35-9 (E)-4-bromo-N-((dimethylamino)methylene)-3-fluorobenzamide 
• 845306-20-9 C₁₁H₁₂BrFN₂O 
• 845306-19-6 5-(4-bromo-3-fluorophenyl)-3-methyl-1,2,4-oxadiazole 
• 945244-57-5 5'-(1-(benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-2-fluoro-2'-methylbiphenyl-4-carboxamide 

Relevant academic research and scientific papers

As opioid receptor antagonists or inverse agonists of the novel compounds

Novel compounds which are antagonists or inverse agonists at one or more of the opioid receptors, pharmaceutical compositions containing them, to processes for their preparation.

SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS

Compounds of Formula I: and salts thereof in which R1, R2, R2a, R3, n, X and ring B have the meanings given in the specification, are inhibitors of mTOR and are useful in the treatment of diseases which are sensitive to inhibition of mTOR, such as cancers.

PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR

The present invention is directed to piperidinyl and piperazinyl derivatives of formula (I) useful as inhibitors of the NPY Y2 receptor, pharmaceutical compositions comprising said compounds, processes for the preparation of said compounds and the use of