75955-30-5

Usage

Uses

Used in Pharmaceutical Synthesis:
4-amino-2-methoxybenzamide is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with diverse therapeutic applications.
Used in Antiviral and Antibacterial Applications:
In the medical field, 4-amino-2-methoxybenzamide is used as an antiviral and antibacterial agent due to its inherent properties that help combat viral and bacterial infections.
Used in Gastrointestinal Disorder Treatment:
4-amino-2-methoxybenzamide is utilized as a potential treatment for gastrointestinal disorders, leveraging its capacity to address specific conditions and improve patient outcomes.
Used as an Enzyme Inhibitor:
In the realm of biochemistry and pharmacology, 4-amino-2-methoxybenzamide serves as an enzyme inhibitor, playing a crucial role in modulating enzymatic activities for therapeutic benefits.
These applications highlight the multifaceted utility of 4-amino-2-methoxybenzamide in various industries, particularly in pharmaceuticals, where its unique properties are harnessed to advance treatment options and improve health outcomes.

Upstream product

• 62726-03-8 2-methoxy-4-nitrobenzamide 
• 39787-83-2 2-methoxy-4-nitrobenzoyl chloride 
• 609784-55-6 4-(benzylamino)-2-methoxybenzamide 
• 619-19-2 2-hydroxy-4-nitrobenzoic acid 
• 2597-56-0 4-nitro-o-anisic acid 
• 101084-96-2 2-methoxy-4-nitrobenzonitrile 
• 609784-58-9 methyl 4-(benzylamino)-2-methoxybenzoate 
• 27492-84-8 Methyl 4-amino-2-methoxybenzoate 

Downstream Products

• 1319746-22-9 (Z)-2-methoxy-4-((1-(2-methoxy-4-nitrophenyl)-5-methyl-1-oxohex-2-en-3-yl)amino)benzamide 
• 1319746-31-0 (Z)-4-((1-(4-amino-2-methoxyphenyl)-5-methyl-1-oxohex-2-en-3-yl)amino)-2-methoxybenzamide 
• 1319746-25-2 (Z)-4-((1-(2-isopropoxy-4-nitrophenyl)-5-methyl-1-oxohex-2-en-3-yl)amino)-2-methoxybenzamide 
• 1319746-34-3 (Z)-4-((1-(4-amino-2-isopropoxyphenyl)-5-methyl-1-oxohex-2-en-3-yl)amino)-2-methoxybenzamide 
• 1319746-28-5 (Z)-4-((1-(2-(benzyloxy)-4-nitrophenyl)-5-methyl-1-oxohex-2-en-3-yl)amino)-2-methoxybenzamide 
• 1319746-37-6 (Z)-4-((1-(4-amino-2-(benzyloxy)phenyl)-5-methyl-1-oxohex-2-en-3-yl)amino)-2-methoxybenzamide 
• 609811-57-6 4-[(1-benzoylpiperidin-4-yl)amino]-2-methoxybenzamide 
• 609784-61-4 2-methoxy-4-[(1-methylpiperidin-4-yl)amino]benzamide 

Relevant academic research and scientific papers

SUBSTITUTED OXOPYRIDINE DERIVATIVES

The invention relates to substituted oxopyridine derivatives and to processes for preparation thereof, and also to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

TANK-BINDING KINASE INHIBITOR COMPOUNDS

Compounds having the following formula (I) and methods of their use and preparation are disclosed:

Oligophenylenaminones as scaffolds for α-helix mimicry

The design and synthesis of small molecule α-helix mimetics has been a productive field over the past decade. These compounds have performed well in a variety of biological systems as functional disruptors of α-helix- mediated protein-protein interactions. In our studies we have continued to develop novel, more biologically compatible scaffolds, which are often easier to assemble and capable of mimicking longer and/or more diverse helices. To this end, we have constructed a new series of i, i+4, i+7 α-helix mimics based on the enaminone scaffold. These molecules represent a step forward in the pursuit of idealized monofacial α-helix mimetics.

BENZAMIDE DERIVATIVES

A compound represented by formula (1): wherein X is a single bond or a substituted or unsubstituted lower alkylene group; Z is a saturated or unsaturated monocyclic hydrocarbon ring group or the like; and each of R1, R2, R3 and R4, which may be the same or different, is a hydrogen atom, a halogen atom, a nitro group, a cyano group, a carboxyl group, a substituted or unsubstituted alkyl group, or the like, a prodrug of said compound, or a pharmaceutically acceptable salt of said compound or prodrug has inhibitory effect on Rho kinase and hence is useful for treating diseases which are such that morbidity due to them is expected to be improved by inhibition of Rho kinase and secondary effects such as inhibition of the Na+/H+ exchange transport system caused by the Rho kinase inhibition, for example, hypertension.