7596-80-7

Basic information

• Product Name: 1,2-BIS(METHANESULFONAMIDO)BENZENE
• Synonyms: 1,2-BIS(METHANESULFONAMIDO)BENZENE;NSC18794;N-{2-[(methylsulfonyl)amino]phenyl}methanesulfonamide;N,N′-(1,2-Phenylene)dimethanesulfonamide;N-[2-(methanesulfonamido)phenyl]methanesulfonamide
• CAS NO: 7596-80-7
• Molecular Formula: C₈H₁₂N₂O₄S₂
• Molecular Weight: 264.32
• Mol File: 7596-80-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 211-214°C
• Boiling Point: 423.5 °C at 760 mmHg
• Flash Point: 209.9 °C
• Appearance: /
• Density: 1.551 g/cm³
• Vapor Pressure: 2.23E-07mmHg at 25°C
• Refractive Index: 1.634
• CAS DataBase Reference: 1,2-BIS(METHANESULFONAMIDO)BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-BIS(METHANESULFONAMIDO)BENZENE(7596-80-7)
• EPA Substance Registry System: 1,2-BIS(METHANESULFONAMIDO)BENZENE(7596-80-7)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 7596-80-7(Hazardous Substances Data)

Usage

General Description

1,2-BIS(METHANESULFONAMIDO)BENZENE is a chemical compound that is commonly used as a reagent in organic synthesis. It is a white crystalline solid that is soluble in water and has a molecular formula of C14H18N2O6S2. 1,2-BIS(METHANESULFONAMIDO)BENZENE is primarily used as a protecting group for alcohols and amines in organic reactions. It is also used as a building block for the synthesis of various pharmaceuticals and agrochemicals. 1,2-BIS(METHANESULFONAMIDO)BENZENE is considered to be relatively safe when handled and used in a laboratory setting, but proper precautions should still be taken to avoid exposure to this compound.

InChI:InChI=1/C8H12N2O4S2/c1-15(11,12)9-7-5-3-4-6-8(7)10-16(2,13)14/h3-6,9-10H,1-2H3

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 95-54-5 1,2-diamino-benzene 

Downstream Products

• 135299-16-0 N-2'-hydroxyethyl-1,2-bis(mesylamide)-benzene 
• 135299-17-1 N,N'-bis(2'-hydroxyethyl)-1,2-bis(mesylamide)-benzene 

Relevant articles and documents

High-Spin Cobalt(II) Complex with Record-Breaking Anisotropy of the Magnetic Susceptibility According to Paramagnetic NMR Spectroscopy Data

Abstract: The tetrahedral cobalt(II) complex [CoL2](HNEt3)2 (I), where L is 1,2-bis(methanesulfonamido)benzene, exhibiting the properties of a single-molecule magnet is synthesized and characterized. The electronic structu

Pd(II)-Catalyzed Aerobic Intermolecular 1,2-Diamination of Conjugated Dienes: A Regio- and Chemoselective [4 + 2] Annulation for the Synthesis of Tetrahydroquinoxalines

A Pd(II)-catalyzed aerobic intermolecular 1,2-diamination of conjugated dienes was developed for the regio- and chemoselective preparation of a variety of functionalized tetrahydroquinoxalines, using simple sulfonyl protected o-phenylendiamines as a nitrogen source. This methodology provides a direct and efficient synthesis of tetrahydroquinoxalines. O2 was used as the stoichiometric oxidant, and reaction conditions were applied to a series of o-phenylendiamines and conjugated dienes. 35 examples are described, and good yields and selectivities are obtained for the majority of the products.

PREPARATION OF INTERMEDIATE PRODUCTS FOR SYNTHESIS OF HETEROMACROCYCLIC COMPOUNDS. PART II. TOSYL ESTERS OF N,N'-BIS(2'-HYDROXYETHYL)-N,N'-BIS(BENZENESULFONYL)-DIAMINES

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