75997-46-5Relevant academic research and scientific papers
NEW SYNTHESIS OF 1,3-DIMETHYL-7-HYDROXYPYRROLOPYRIMIDINE-2,4(1H,3H)-DIONES (9-HYDROXY-9-DEAZATHEOPHYLLINES)
Yoneda, Fumio,Motokura, Miyuki,Otagiri, Masaki
, p. 1273 - 1276 (2007/10/02)
Treatment of 5-nitro-1,3,6-trinitrouracil with aryl aldehydes in the presence of piperidine causes the condensation to the 5-nitro-6-styryl-uracil derivatives, followed by the intramolecular cyclization including piperidine-catalyzed oxidation-reduction t
Syntheses of 9-Deazatheophyllines and 6-Deoxy-9-deazatheophyllines
Nishigaki, Sadao,Kanamori, Yukako,Senga, Keitaro
, p. 1636 - 1641 (2007/10/02)
The reaction of 1,3-dimethyl-5-nitro-6-styryluracils (IIa-e) with sodium dithionite in formic acid afforded the corresponding 8-aryl-9-deazatheophyllines (IVa-e).The reaction of IVa with phosphorus oxychloride gave 6-chloro-6-deoxy-8-phenyl-9-deazatheophy
