75999-00-7 Usage
Uses
Used in Pharmaceutical Industry:
Trimethoprim is used as an antibiotic for treating a variety of bacterial infections. Its mechanism of action involves the inhibition of tetrahydrofolic acid synthesis, disrupting bacterial folate metabolism and leading to the inhibition of bacterial growth and eventual death.
Used in Combination Therapy:
Trimethoprim is often used in combination with sulfamethoxazole, creating a synergistic effect that enhances the treatment of various infections. This combination is particularly effective against urinary tract infections, respiratory infections, and certain types of pneumonia, providing a broader spectrum of antibacterial activity.
Check Digit Verification of cas no
The CAS Registry Mumber 75999-00-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,9,9 and 9 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 75999-00:
(7*7)+(6*5)+(5*9)+(4*9)+(3*9)+(2*0)+(1*0)=187
187 % 10 = 7
So 75999-00-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H16N2O/c1-9-13(10(2)15(3)14-9)8-11-4-6-12(16)7-5-11/h4-7,16H,8H2,1-3H3
75999-00-7Relevant academic research and scientific papers
Simple Synthesis of 4-(Heteroarylmethyl)phenols and Their Acylation
Kuebel, Boerries
, p. 1392 - 1401 (2007/10/02)
Condensation of 4-hydroxybenzaldehyde (1) with ethyl acetoacetate (2a) or acetylacetone (2b) gives 3a and 3b, respectively, which on hydrogenation afford the 2-(4-hydroxybenzyl)-1,3-dicarbonyl compounds 4a and 4b, respectively.These react with hydrazines
