760-80-5

Basic information

• Product Name: ETHYL 2-FLUOROACRYLATE
• Synonyms: ETHYL 2-FLUOROACRYLATE;2-Fluoroethyl acrylate 97%;2-Fluoroethylacrylate97%;2-FLUOROPROPENOIC ACID ETHYL ESTER;2-Propenoic acid, 2-fluoro-, ethyl ester;Ethyl alpha-fluoroacrylate
• CAS NO: 760-80-5
• Molecular Formula: C₅H₇FO₂
• Molecular Weight: 118.11
• Product Categories: monomer
• Mol File: 760-80-5.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 109°C
• Flash Point: 18.2 °C
• Appearance: /
• Density: 1.056
• Vapor Pressure: 29.5mmHg at 25°C
• Refractive Index: 1.381
• Sensitive: Lachrymatory
• CAS DataBase Reference: ETHYL 2-FLUOROACRYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-FLUOROACRYLATE(760-80-5)
• EPA Substance Registry System: ETHYL 2-FLUOROACRYLATE(760-80-5)

Safety Data

• Hazard Codes: Xi,F
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: KEEP COLD, FLAMMABLE
• Hazardous Substances Data: 760-80-5(Hazardous Substances Data)

Usage

Hazards

MFA is highly?flammable?and can be harmful if inhaled, in contact with?skin, or if swallowed. It is irritating to?eyes,?respiratory system, and skin.

Description

Methyl 2-fluoroacrylate (MFA) is a chemical compound classified as an acrylate ester. The molecular formula is C4H5FO2 and the molecular weight is 104.08. The systematic name of this chemical is methyl 2-fluoroprop-2-enoate.

InChI:InChI=1/C5H7FO2/c1-3-8-5(7)4(2)6/h2-3H2,1H3

Upstream product

• 50-00-0 formaldehyd 
• 459-72-3 ethyl 2-fluoroacetate 
• 1993-92-6 2-fluoro-3-hydroxypropionic acid ethyl ester 
• 2927-18-6 α,β-Dibrom-α-fluor-propionsaeure-aethylester 
• 2356-16-3 ethyl(diethylphosphono)(fluoro)acetate 
• 108221-67-6 ethyl 2-bromo-2-fluoropropionate 
• 910803-66-6 ethyl α-(1,3-benzothiazol-2-ylsulfonyl)-α-fluoroacetate 
• 623-47-2 propynoic acid ethyl ester 
• 756-31-0 diethyl 2-fluoro-2-(hydroxymethyl)malonate 
• 1428-46-2 diethyl 2-fluoro-2-chloromethylmalonate 
• 2710-86-3 Diaethyl-α-fluor-α-methansulfonyloxymethyl-malonat 
• 64-17-5 ethanol 
• 420-25-7 1-bromo-1-fluoroethylene 
• 201230-82-2 carbon monoxide 

Downstream Products

• 34139-20-3 Ethyl-α,α-difluoro-β-nitropropionat 
• 57975-70-9 3-Cyclohexylamino-2-fluoro-propionic acid ethyl ester 
• 1743-71-1 2-Fluor-4-ethoxycarbonyl-glutarsaeure-diethylester 
• 1652-64-8 C-Acetamino-C-<2-fluor-2-aethoxycarbonyl-aethyl>-malonsaeure-diaethylester 
• 344905-88-0 ethyl 3-[ethoxy(methyl)phosphoryl]-2-fluoropropanoate 
• 344413-71-4 ethyl 3-[(diethoxymethyl)(ethoxy)phosphoryl]-2-fluoropropanoate 
• 32273-86-2 (±)-ethyl 1-fluorocyclohex-3-enecarboxylate 
• 1378386-19-6 N-(n-propyl)-α-fluoroacrylamide 
• 74893-46-2 2-fluoroprop-2-enoyloxysodium 
• 430-99-9 2-fluoroacrylic acid 
• 33666-37-4 (+/-)-1-Fluor-2,2-diphenylcyclopropancarbonsaeureaethylester 
• 42909-49-9 3-Chloro-2-fluoro-2-phenylsulfanyl-propionic acid ethyl ester 
• 42909-50-2 2-Chloro-2-fluoro-3-phenylsulfanyl-propionic acid ethyl ester 
• 34139-17-8 α-Fluoro-β-acetylmercaptopropionsaeureethylester 

Relevant articles and documents

PREPARATION OF ETHYL 2-FLUOROACRYLATE, CH2=CFCOOEt

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Preparation method of alpha-fluorinated acrylate

The invention discloses a method for preparing alpha-fluorinated acrylate.The method comprises the steps that raw materials are dissolved into a first organic solvent at first, organic base or inorganic base is added, a hydroxyl protecting agent is added dropwisely on the condition of low temperature ranging from subzero 10 DEG C to 10 DEG C, the temperature is slowly increased to the room temperature to 100 DEG C after dropwise addition is completed, a heat preservation reaction is performed for 3-6 h, water is added for dissolving solids for organic phase washing and liquid separation, an organic phase is concentrated to be dry, the product is added into a second organic solvent, a polymerization inhibitor is added, heating is performed to reach 100-180 DEG C, a reaction is performed for 1-18 h, a mixed solution containing the product is distilled out, and then distillation purification is performed to obtain the alpha-fluorinated acrylate.The method is low in cost, easy to implement and low in equipment requirement, no extremely toxic substance is adopted as raw materials, the whole process is environmentally friendly, the yield is high, the product purity is good, and the method has economic value and is suitable for industrialization.

Method for the preparation of compounds

The invention provides a preparation method of a compound as described in the formula 1. The method comprises the steps of (1) contacting a compound as described in the formula 2 and a compound as described in the formula 3 in the existence of alkali to obtain a compound as described in the formula 4; and (2) directly contacting a reaction product obtained in the step (1) and paraformaldehyde to obtain the compound as described in the formula 1, wherein weak acid is added in the reaction product before the reaction product obtained in the step (1) is in contact with the paraformaldehyde so that the residual alkali in the reaction product can be neutralized. By using the method, the compound as described in the formula 1 can be effectively prepared.