76002-83-0Relevant academic research and scientific papers
TLR (Toll-like receptor) modulators, pharmaceutical composition thereof, preparation method and application
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Paragraph 0082; 0083; 0084, (2018/12/05)
The invention belongs to the field of pharmaceutical chemistry, particularly relates to compounds with TLR (Toll-like receptor) modulation effect as well as a preparation method and an application ofthe compounds, and provides compounds represented by the following formula X in the description. The compounds of formula X can be used as the TLR modulators and have higher activity. Besides, the compounds have the characteristics of high efficiency, low toxicity, resistance to drug resistance and the like, and have clinical application value. Moreover, synthesis steps of the compounds are simple, so that the compounds have higher economic utilization value.
