7601-99-2

Usage

Uses

Used in Pharmaceutical Industry:
Bromodifluoroacetonitrile is utilized as an intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique chemical properties make it a valuable component in the creation of medicinal compounds.
Used in Agrochemical Industry:
BROMODIFLUOROACETONITRILE also serves as an intermediate in the production of agrochemicals, specifically in the manufacturing of pesticides and herbicides. Bromodifluoroacetonitrile plays a crucial role in enhancing crop protection and managing pests and weeds in agricultural settings.
Used in Organic Synthesis:
Bromodifluoroacetonitrile is employed as a building block in organic synthesis, allowing for the creation of a wide range of organic compounds with diverse applications across various industries.

InChI:InChI=1/C2BrF2N/c3-2(4,5)1-6

Upstream product

• 2169-67-7 2-bromo-2,2-difluoroacetamide 
• 75-61-6 dibromodifluoromethane 
• 544-92-3 copper(I) cyanide 

Downstream Products

• 667-27-6 Ethyl bromodifluoroacetate 

Relevant academic research and scientific papers

Preparation method of ethyl bromodifluoroacetate

The invention belongs to the field of organic synthesis and discloses a preparation method of ethyl bromodifluoroacetate. Difluorobromoacetonitrile is taken as a raw material, and prepared through a one-pot method and subjected to alcoholysis and esterification in ethanol aqueous solution to obtain ethyl bromodifluoroacetate. According to the method provided by the invention, difluorobromoacetonitrile is taken as the raw material and then bromodifluoroacetic acid is subjected to the alcoholysis and esterification after directly hydrolyzed, without generating a toxic bromodifluoroacetyl halide intermediate, and the use of fuming sulfuric acid as an oxidant and bad in operating environments and maximum in pollution, or peroxide or ozone, or oxygen in a high pressure system to result in poor selectivity and very low yield is avoided. Furthermore, the existence of by-products with extremely strong hydrogen halide corrosion of hydrogen fluoride and the like which both have extremely large corrosion to metal and glass-lined materials is avoided in the process, so that the requirements for production reaction equipment are lowered, and the preparation of ethyl bromodifluoroacetate can be carried out in the ordinary glass-lined reaction device.