76041-09-3

Upstream product

• 446302-83-6 1-N-benzyl-3-phenyl-4-piperidone 
• 22286-82-4 2-phenyl-acrylic acid ethyl ester 
• 101-97-3 Ethyl 2-phenylethanoate 
• 22319-48-8 ethyl 2-phenyl-3-(N-benzylamino)propionate 
• 632352-54-6 3-[benzyl-(2-ethoxycarbonyl-ethyl)-amino]-2-phenyl-propionic acid ethy ester 
• 76041-06-0 ethyl 3-[(2-ethoxycarbonyl)ethylamino]-2-phenylpropionate 
• 1096168-16-9 4-oxo-5-phenyl-piperidine-3-carboxylic acid ethyl ester 

Downstream Products

• 632353-48-1 N-ethyl-4-oxo-3-phenylpiperidine-1-carboxamide 
• 1096168-17-0 3-phenyl-5-[1-pyridin-2-yl-methylidene]-piperidin-4-one 
• 1096167-32-6 1-(2,4-dihydroxy-benzenesulfonyl)-3-phenyl-5-[1-pyridin-2-ymethylidene]-piperidin-4-one 

Relevant academic research and scientific papers

NOVEL SUBSTITUTED PIPERIDONES AS HSP INDUCERS

The present invention relates to novel compounds of formula (I) or (II), their pharmaceutically acceptable salts and their hydrates, solvates, stereoisomers, conformers, tautomers, polymorphs and prodrugs and also pharmaceutically acceptable compositions containing them Wherein R1, R2, R3, R4, R5, R6 and R7 are as defined in the specification. The compounds of the present invention are HSP inducers and by virtue of this effect, useful for the treatment of various diseases accompanying pathological stress. The present invention also relates to a process for the preparation of the said novel compounds. The invention also relates to the use of the above-mentioned compounds for the preparation of medicament for use as pharmaceuticals.

Synthesis of 3-phenyl-4-piperidones from acetophenone by shapiro and azamichael reactions and their further derivatization

The Shapiro reaction of acetophenone is the key in a convenient three-step access to a divinyl ketone which is further transformed by double aza-Michael reactions with primary amines into N-substituted 3-phenyl-4-piperidones. In the case of N-benzyl and N

PIPERIDINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE

The present invention provides a compound represented by the formula: ???wherein Ar is an aryl group, an aralkyl group or an aromatic heterocyclic group, each of which may be substituted, R1 is a hydrogen atom, an optionally substituted hydroca

Antidepressive and analgesic 4-aryloxy- and 4-arylthio-3-phenylpiperidines

Novel 4-aryloxy- and 4-arylthio-3-phenylpiperidines and related compounds, physiologically acceptable salts thereof and intermediates therefor possessing analgesic, antidepressant properties, and a process for the preparation of such compounds, derivatives and intermediates are described.