76047-28-4

Upstream product

• 455-18-5 4-CF₃C₆H₄CN 
• 75-05-8 acetonitrile 

Downstream Products

• 76047-29-5 3-(p-chlorophenyl)-5-(β-amino-p-trifluoromethylstyryl)-1,2,4-oxadiazole 
• 76047-46-6 2-[3-(4-Chloro-phenyl)-[1,2,4]oxadiazol-5-yl]-1-(4-trifluoromethyl-phenyl)-ethanone 
• 76047-38-6 2-[3-(4-Nitro-phenyl)-[1,2,4]oxadiazol-5-yl]-1-(4-trifluoromethyl-phenyl)-ethanone 

Relevant academic research and scientific papers

The Reaction of para-Substituted β-Aminocinnamonitriles with Benzonitrile Oxides

β-Aminocinnamonitrile para-substituted by electron-withdrawing groups (5a,b) with benzonitrile oxides (2) give the expected cycloadducts (6) to the C-N triple bond.The p-methyl derivative (5c) behaves similarly, but the yields are smaller.Reactions of (2) with derivatives para-substituted by electron-donating groups (5d,e) give two bis-adducts, the structures of which have been elucidated.