7605-65-4Relevant academic research and scientific papers
Reactions of alkylenebisbromomalonates with nucleophiles
Kostyanovsky, R. G.,Krutius, O. N.,El'natanov, Yu. I.
, p. 2065 - 2069 (1994)
Treatment of alkylenebisbromomalonates with nucleophiles (AcOK, AgOH, KHCO3, 1,8-diazabicycloundec-7-ene, or Ph3P) results mainly in their debromination to give cycloalkane-1,1,2,2-tetracarboxylates.When H2O and acids are present, the reaction gives products of the substitution pf one or two bromine atoms by hydrogen.Alkaline hydrolysis results in oxacycloalkane-α,α,α',α'-tetracarboxylic acids.The reaction mechanism is discussed. - Key words: alkylenebisbromomalonates; nucleophilic and homolytic substitution; cycloalkane-1,1,2,2-tetracarboxylates; oxacycloalkane-α,α,α',α'-tetracarboxylic acid.
