7606-84-0

Usage

Uses

Used in Materials Science:
2,3,5,6-tetraiodoterephthalic acid is utilized as a key component in the development of advanced materials due to its unique chemical structure and properties. The presence of iodine atoms allows for specific interactions and modifications that can improve material characteristics such as stability, processability, and performance in various applications.
Used in Pharmaceuticals:
In the pharmaceutical industry, 2,3,5,6-tetraiodoterephthalic acid serves as an intermediate or building block for the synthesis of pharmaceutical compounds. Its unique properties, including increased solubility, can be leveraged to improve the bioavailability and efficacy of drug molecules, potentially leading to the development of new therapeutic agents.
Used in Organic Synthesis:
2,3,5,6-tetraiodoterephthalic acid is employed as a reagent or catalyst in organic synthesis processes. Its reactivity, stemming from the presence of iodine atoms, can facilitate specific chemical reactions, enabling the synthesis of complex organic compounds with potential applications in various fields, including agrochemicals, dyes, and specialty chemicals.
Overall, the versatility of 2,3,5,6-tetraiodoterephthalic acid, stemming from its unique chemical structure and properties, positions it as a valuable asset in the development of new materials and compounds across multiple industries.

Upstream product

• 100-21-0 terephthalic acid 
• 7664-93-9 sulfuric acid 
• 7553-56-2 iodine 

Downstream Products

• 28719-77-9 tetra-iodoterephthaloyl dichloride 
• 1416249-12-1 [lead(II)(2,3,5,6-tetraiodo-1,4-benzenedicarboxylate (+1H))2(dimethylsulfoxide)4] 
• 1208985-08-3 Cu(II)(2,3,5,6-tetraiodo-1,4-benzenedicarboxylate)(dmf)2 
• 1208985-09-4 Cu(II)(2,3,5,6-tetraiodo-1,4-benzenedicarboxylate)(def)2(H₂O) 

Relevant academic research and scientific papers

Iodinated polymers for biological agent defeat

A binder, and related processes, has been developed for biological agent defeat formulations. This highly iodinated binder is based on the polymer polyethylene tetraiodoterephthalamide. The materials have been formulated with metal fuel particles, such as

Synthesis and characterization of radiopaque poly(ether urethane) with iodine-Containing diol as chain extender

Novel radiopaque iodinated poly(ether urethane) (IPEU) was prepared by using iodine-containing diol as chain extender in a normal two-step condensation polymerization process. This new iodine-containing diol was synthesized by iodination of terephthalic a

Iodinated aroyloxy ketones

Compounds having the structure STR1 wherein (Z--COO is the residue of an iodinated aromatic acid; n is an integer from 0 to 20; R1, R2, R3 and R4 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, halogen, hydroxy, acylamino, acetamidoalkyl, acetamidoaryl, --COO-alkyl, --COO-aryl, --COO-aralkyl, --CO-alkyl, --CO-aryl, --CO-heterocyclyl, cyano or heterocyclyl; R5 is H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxyalkyl, heterocyclyl, or a Z-CO2 -CR1 R2 (CR3 R4)n group, wherein Z, R1, R2, R3, R4 and n are as defined above, m is an integer from 0 to 10, p is an integer from 0 to 10, and m+p≥1 are useful as contrast agents in x-ray imaging compositions and methods.

Iodinated aromatic compounds

Compounds having the structure STR1 wherein (Z--COO is the residue of an iodinated aromatic acid; n is an integer from 0 to 6; R1 and R2 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy or aryloxy; R3 and R4 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, halogen, hydroxy or acylamino; Q represents the atoms necessary to complete a carbocyclic or heterocyclic unsaturated mono- or bicyclic aromatic ring; and R5 is H, alkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, halogen, hydroxy, amino, acylamino, alkoxyalkyl, fluoroalkyl, acetamidoalkyl, COO-alkyl, cyano, carboxamido, sulfonate, sulfonamido, ureido, or carbamyl are useful as contrast agents in x-ray imaging compositions and methods.

Polyiodinated aroyloxy esters

Compounds having the structure STR1 wherein Z--COO)m is the residue of a polyiodinated aromatic acid; m is 1, 2, 3 or 4; n is an integer from 1 to 20; R1 and R2 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy or aryloxy; R3 and R4 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, halogen, hydroxy or acylamino; and R5 is H, alkyl, cycloalkyl, aryl, aralkyl, alkoxyalkyl or acetamidoalkyl; are useful as contrast agents in x-ray imaging compositions and methods.

Iodinated wetting agents

Compounds having the structure STR1 wherein (Z)--COO is the residue of an iodinated aromatic acid; M is H, a cation, --CH2 CH2 O--m H, and --CH2 CH(OH)O--p H; m is an integer from 1 to 150; p is an integer from 1 to 50; and L is one or more divalent linking groups selected from alkylene, cycloalkylene, arylene, arylenealkylene, and alkylenearylene are particularly useful as wetting agents in x-ray imaging compositions.

Iodinated aroyloxy esters

Compounds having the structure STR1 wherein (Z--COO is the residue of an iodinated aromatic acid; n is an integer from 1 to 20; R1 and R2 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy or aryloxy; R3 and R4 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, halogen, hydroxy or acylamino; and R5 is alkyl, cycloalkyl, aryl, aralkyl, alkoxyalkyl or acetamidoalkyl; are useful as contrast agents in x-ray imaging compositions and methods.

Iodinated benzoyl acetals and ketals for x-ray imaging

Compounds having the structure STR1 wherein (Z--COO is the residue of an iodinated aromatic acid; R is alkyl, cycloalkyl, aryl, aralkyl, STR2 or alkenyl; R1 is H, alkyl, cycloalkyl, aryl, aralkyl, or --CH2 --m CO2 R3 ; R2 is H, alkyl, cycloalkyl, aryl, aralkyl, --CH2 --n CO2 R4, or a STR3 group, wherein Z, R and R1 are as defined above; or R1 and R2, taken together with the carbon atom to which they are attached represent cycloalkyl; R3 is H, alkyl, cycloalkyl, aryl or aralkyl; R4 is H, alkyl, cycloalkyl, aryl or aralkyl; and m, n and p are independently an integer of from 0 to 17; provided that R1 and R2 can not both be H; are useful in the preparation of x-ray contrast compositions for medical imaging.

Iodinated aromatic propanedioates

Compounds having the structure STR1 where (Z--COO is the residue of an iodinated aromatic acid; R1 and R2 are independently alkyl, fluoroalkyl, cycloalkyl, aryl or aralkyl; and R3 is H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, cyano, sulfonate, carboxamido, sulfonamido, CO2 -alkyl, CO2 -aryl or CO2 -aralkyl; are useful as contrast agents in x-ray imaging compositions and methods.

Iodinated aroyloxy carboxamides

Compounds having the structure STR1 wherein (Z--COO is the residue of an iodinated aromatic acid; n is an integer from 0 to 20; R1 and R2 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy or aryloxy; R3 and R4 are independently a substituent as defined for R1 and R2 above, halogen, hydroxy or acylamino; and R5 and R6 are independently H, alkyl, cycloalkyl, aryl, aralkyl, alkoxy, alkoxyalkyl, or acetamidoalkyl; or R5 and R6, taken together with the nitrogen atom to which they are attached, represent a 4 to 7-membered nitrogen containing ring, are useful as contrast agents in x-ray imaging compositions and methods.