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• 536-74-3 phenylacetylene 
• 106-89-8 epichlorohydrin 
• 682353-67-9 1,3-diazido-propan-2-one 
• 118712-54-2 glycidyl p-toluenesulfonate 
• 57011-48-0 1,3-diazido 2-propanol 

Relevant academic research and scientific papers

A chiral salen-based MOF catalytic material with high thermal, aqueous and chemical stabilities

A highly stable chiral salen-based metal-organic framework [(Cu4I4)2L4]·20DMF·3CH3CN (1) [L = (R,R)-N,N′-bis(3-tert-butyl-5-(4-pyridyl)salicylidene)-1,2-diphenylethylenediamine nickel(ii)] has been sy

Structural and theoretical studies of 1,3-Bis-(1,2,3-triazol-1-yl)-propan-2-ol derivatives.

The crystal structure of three 1,3-Bis-(1,2,3-triazol-1-yl)-propan-2-ol derivatives was determined by X-ray diffraction analyses. The studied compounds presented O[sbnd]H???N hydrogen bonds between hydroxyl group of one molecule with triazolyl nitrogen at

Copper@PMO nanocomposites as a novel reusable heterogeneous catalyst for microwave-assisted green synthesis of β-hydroxy-1,2,3-triazoles through experimental design protocol

A microwave-assisted multicomponent reaction was used to prepare a series of β-hydroxy-1,2,3-triazoles in the presence of copper@PMO nanocomposites as a catalyst. Box-Behnken design and response surface methodology were used to optimize the influencing pa

CuO–NiO bimetallic nanoparticles supported on graphitic carbon nitride with enhanced catalytic performance for the synthesis of 1,2,3-triazoles, bis-1,2,3-triazoles, and tetrazoles in parts per million level

The unification of CuCl2·2H2O and NiCl2·6H2O with the support of graphitic carbon nitride yielded to form an efficient, synergistic, bimetallic nano-catalyst CuO–NiO@g-C3N4. FT-IR, SEM, TEM

Click reactions catalyzed by Cu(I) complexes supported with dihydrobis(2-mercapto-benzimidazolyl)borate and phosphine ligands

Four Cu(I) complexes bearing dihydrobis(2-mercapto-benzimidazolyl)borate and phosphine co-ligands were synthesized and their catalytic activity was investigated in azide-alkyne reactions. These complexes were tested as catalyst system and among them a Cu(

Synthesis and evaluation of antifungal and antitrypanosomastid activities of symmetrical 1,4-disubstituted-1,2,3-bistriazoles obtained by CuAAC conditions

Background: The trypanosomatids, such as the protozoan Leishmania spp., have a demand by ergosterol, which is not present in the membrane from mammal cells. The suppression of the synthesis of ergosterol would be a new target of compounds with leishmanici

Functionalized polytriazoles on graphene oxide-supported copper(I) complex as an effective reusable catalyst for sonochemical click synthesis of triazoles in aqueous media

In the present study, a copper complex immobilized on graphene oxide was synthesized as a novel, green, highly efficient and reusable heterogeneous catalyst. Then, the synthesis of β-hydroxy-1,2,3-triazole derivatives were performed by the employment of G

Immobilized polytriazole complexes of copper(I) onto graphene oxide as a recyclable nanocatalyst for synthesis of triazoles

An efficient solid-supported catalyst for the Huisgen [3?+?2] cycloaddition reaction between azides and alkynes was prepared from copper(I) iodide and 1,2,3-triazole-functionalized graphene oxide. This catalyst was then used for the efficient synthesis of

Hydrotrope promoted in situ azidonation followed by copper catalyzed regioselective synthesis of β-hydroxytriazoles

Abstract: The rapid method for the synthesis of organic azides was achieved by employing azide acceptors such as halides, epoxides and pseudohalides like diazonium salts and aryl boronic acids in hydrotropic media. In extension, the sequential multicomponent reaction of epoxides, azide and alkynes using copper catalysis has been discussed. The reaction proceeds via the in situ generation of azido-alcohol followed by synthesis of chiral β-hydroxytriazoles. This [3?+?2] cycloaddition reaction of azide and alkyne using copper catalysis serves as a green and efficient protocol in “Click Chemistry”. The nucleophilic addition of azide to epoxide and alkyne-azide cycloaddition is the two simultaneous regioselective click reactions observed in the proposed method. Graphical Abstract: [Figure not available: see fulltext.].

Cu ion-exchanged and Cu nanoparticles decorated mesoporous ZSM-5 catalysts for the activation and utilization of phenylacetylene in a sustainable chemical synthesis

Mesoporous ZSM-5 was synthesized using a 1,4-diazabicyclo[2.2.2]octane based multi-cationic surfactant as a structure directing agent. Cu2+ exchanged mesoporous ZSM-5 was prepared by the ion-exchange process. Cu nanoparticles decorated mesoporous ZSM-5 was prepared using NaBH4 as a reducing agent. Materials were characterized by the complementary combination of X-ray diffraction, N2-adsorption, UV-visible, and scanning/transmission electron microscopic techniques. For comparative purposes, Cu2+ exchanged ZSM-5, HY, and NaY; and Cu nanoparticles decorated conventional ZSM-5, SBA-15, and Al2O3 samples were also prepared. A sustainable catalytic process was developed for the selective synthesis of indolizine, chalcone, and triazole derivatives using a mesoporous ZSM-5 based heterogeneous catalyst. A multi-component synthetic strategy is reported here for the selective synthesis of the above mentioned chemicals that involves phenylacetylene as one of the building blocks. Control experiments were performed to ascertain the proposed reaction pathways. Recycling and leaching experiments were performed to demonstrate the sustainability and robustness of the catalytic process. Among these catalysts, Cu nanoparticles decorated mesoporous ZSM-5 exhibited the highest activity in all these reactions. The catalyst was found to be highly stable and it was possible to recycle the catalyst five times with no appreciable loss in the activity. A wide range of indolizine, chalcone, and 1,2,3-triazole derivatives were prepared in high yields using this catalyst.