760968-77-2

Upstream product

• 1882-72-0 methyl 2-amino-5-hydroxybenzoate 
• 98-59-9 p-toluenesulfonyl chloride 
• 394-31-0 2-amino-5-hydroxybenzoic acid 

Downstream Products

• 951668-12-5 5-(4-Cyanophenoxy)-2-(toluene-4-sulfonylamino)-benzoic acid methyl ester 
• 951667-56-4 5-(4-nitro-3-methoxy-phenoxy)-2-(toluene-4-sulfonylamino)-benzoic acid methyl ester 
• 951665-99-9 5-(3-Benzyloxy-4-nitrophenoxy)-2-(toluene-4-sulfonylamino)benzoic acid methyl ester 
• 951667-42-8 5-(3-chloro-4-nitro-phenoxy)-2-(toluene-4-sulfonylamino)-benzoic acid methyl ester 
• 951666-56-1 5-(3-ethylamino-4-nitro-phenoxy)-2-(toluene-4-sulfonylamino)-benzoic acid methyl ester 
• 951667-76-8 5-(4-nitro-3-vinyl-phenoxy)-2-(toluene-4-sulfonylamino)-benzoic acid methyl ester 
• 951667-49-5 5-[3-cyano-4-nitro-phenoxy]-2-(toluene-4-sulfonyl-amino)-benzoic acid methyl ester 
• 951667-05-3 5-(3-methyl-4-nitro-phenoxy)-2-(toluene-4-sulfonylamino)-benzoic acid methyl ester 
• 951668-00-1 5-(4-nitro-3-propylamino-phenoxy)-2-(toluene-4-sulfonylamino)-benzoic acid methyl ester 
• 951667-63-3 5-(3-Ethoxy-4-nitro-phenoxy)-2-(toluene-4-sulfonyl-amino)-benzoic acid methyl ester 
• 951666-18-5 5-(4-nitro-3-pentyloxy-phenoxy)-2-(toluene-4-sulfonylamino)-benzoic acid methyl ester 
• 951666-31-2 5-(3-Isobutoxy-4-nitro-phenoxy)-2-(toluene-4-sulfonylamino)-benzoic acid methyl ester 
• 951666-64-1 5-(3-benzyl-4-nitro-phenoxy)-2-(toluene-4-sulfonylamino)-benzoic acid methyl ester 
• 951667-70-2 5-(4-nitro-3-propoxy-phenoxy)-2-(toluene-4-sulfonylamino)-benzoic acid methyl ester 

Relevant academic research and scientific papers

Organocatalytic Atroposelective Arylation of 2-Naphthylamines as a Practical Approach to Axially Chiral Biaryl Amino Alcohols

The first phosphoric acid catalyzed direct arylation of 2-naphthylamines with iminoquinones for the atroposelective synthesis of axially chiral biaryl amino alcohols has been developed. This reaction constitutes a highly functional-group-tolerant route for the rapid construction of enantioenriched axially chiral biaryl amino alcohols, and is a rare example of 2-naphthylamines acting as nucleophiles in an organocatalytic enantioselective transformation. Furthermore, the products, which feature various halogen atoms, provide access to structurally diverse axially chiral amino alcohols through further transformations.

HOMOGENEOUS TIME RESOLVED FLUORESCENCE BASED TEST SYSTEM

The present invention concerns a fluorescence resonance energy transfer based high throughput test system to measure the formation of the HIV gp41 six-helix bundle. In a first embodiment the current invention relates to a homogeneous time resolved fluorescence-based test system comprising a first helical polypeptide consisting essentially of the sequence of IQN36 (SEQ ID NO:1); a second helical polypeptide consisting essentially of the sequence of C34 (SEQ ID NO: 2) wherein said IQN36 is labeled with a light emitting fluorophore and said C34 is labeled with an ultra-violet excitable fluorophore.

New synthesis of a pyrroloquinoline skeleton, the martinelline core, using a tandem Michael-aldol strategy

The pyrroloquinoline moiety of Martinelline, a naturally occurring bradykinin receptor antagonist, has been synthesized from 1,2-dihydroquinoline which was prepared by using a tandem Michael-aldol reaction as a key step.

Synthetic studies on bradykinin antagonist martinellines: Construction of a pyrrolo[3,2-c]quinoline skeleton using silicon-tether RCM reaction and allylic amination

The pyrrolo[3,2-c]quinoline consisting of a core structure of martinellines, the first naturally occurring heterocycle, was prepared through silicon-tether ring-closing metathesis reaction and intramolecular allylic amination as key steps. Graphical Abstr

Asymmetric synthesis of tetrahydroquinoline derivative, a building block of martinellines, via intramolecular allylic amination using 9-PBN

A tetrahydroquinoline derivative, a core structure of martinellines, was prepared through intramolecular allylic amination of the racemic precursor with a stereogenic center using 9-PBN and palladium. The reaction proceeded in a reagent-controlled manner