760987-56-2

Upstream product

• 760987-76-6 (2-azido-3,4,6-tri-O-benzyl-2-deoxy-α-D-glucopyranosyl)-(1->6)-1-O-allyl-3,4,5-tri-O-benzyl-2-O-hexadecanoyl-D-myo-inositol 
• 100-39-0 benzyl bromide 
• 202845-42-9 1-O-allyl-3,4,5-tri-O-benzyl-D-myo-inositol 
• 760987-74-4 1-O-allyl-3,4,5-tri-O-benzyl-2-O-(4-bromobenzyl)-D-myo-inositol 
• 760987-75-5 (2-azido-2-deoxy-α-D-glucopyranosyl)-(1->6)-1-O-allyl-3,4,5-tri-O-benzyl-2-O-(4-bromobenzyl)-D-myo-inositol 
• 760987-55-1 O-(2-azido-3,4,6-tri-O-benzyl-2-deoxy-α-D-glucopyranosyl)-(1->6)-1-O-allyl-3,4,6-tri-O-benzyl-D-myo-inositol 
• 760987-43-7 (2-azido-3,4,6-tri-O-benzyl-2-deoxy-α-D-glucopyranosyl)-(1->6)-1-O-allyl-3,4,5-tri-O-benzyl-2-O-(4-bromobenzyl)-D-myo-inositol 
• 1053696-21-1 (2R,3R,4R,5S,6R)-2-[(1S,2R,3S,4S,5R,6S)-2-Allyloxy-4,5,6-tris-benzyloxy-3-(3',4'-dimethoxy-biphenyl-4-ylmethoxy)-cyclohexyloxy]-3-azido-4,5-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran 
• 133163-53-8 O-(2-azido-3,4,6-tri-O-benzyl-2-deoxy-α-D-glucopyranosyl)-(1->4)-1,5,6-tri-O-benzyl-L-myo-inositol 
• 68275-40-1 trimethyl orthohexadecanoate 

Downstream Products

• 1035456-81-5 2-azido-3,4,6-tri-O-benzyl-2-deoxy-α-D-glucopyranosyl-(1-6)-3,4,5-tri-O-benzyl-1-O-(dibenzylphosphono)-2-palmitoyl-D-myo-inositol 
• 1035456-82-6 2-amino-3,4,6-tri-O-benzyl-2-deoxy-α-D-glucopyranosyl-(1-6)-3,4,5-tri-O-benzyl-1-O-(phosphono)-2-palmitoyl-D-myo-inositol lactam 
• 1035456-83-7 2-Amino-2-deoxy-α-D-glucopyranosyl-(1-6)-2-palmitoyl-D-myo-inositol 

Relevant academic research and scientific papers

SYNTHETIC LIPOPHILIC INOSITOL GLYCANS FOR TREATMENT OF CANCER AND GLUCOSE-METABOLISM DISORDERS

The present intervention related to materials and methods for the synthesis of lipophilic inositol glycan compounds, and salts, solvates and physiological functional derivatives thereof, and their use for the treatment of cancer and glucose-metabolism disorders, such as, for example, diabetes, obesity and metabolic syndrome.

A Suzuki-Miyaura coupling mediated deprotection as key to the synthesis of a fully lipidated malarial GPI disaccharide

Ligandless palladium-catalyzed Suzuki-Miyaura coupling converted an inert p-bromobenzyl ether to a DDQ-labile p-(3,4-dimethoxyphenyl) benzyl ether in the presence of azide functionality and this strategy serves as a key step for the convergent synthesis of a fully lipidated malaria GPI disaccharide.