760990-49-6

Basic information

• Product Name: 1H-Inden-1-one, 2-(4-bromobenzoyl)-2,3-dihydro-5,6-dimethoxy-
• CAS NO: 760990-49-6
• Molecular Formula: C18H15BrO4
• Molecular Weight: 375.219
• Mol File: 760990-49-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-Inden-1-one, 2-(4-bromobenzoyl)-2,3-dihydro-5,6-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Inden-1-one, 2-(4-bromobenzoyl)-2,3-dihydro-5,6-dimethoxy-(760990-49-6)
• EPA Substance Registry System: 1H-Inden-1-one, 2-(4-bromobenzoyl)-2,3-dihydro-5,6-dimethoxy-(760990-49-6)

Safety Data

• Hazardous Substances Data: 760990-49-6(Hazardous Substances Data)

Upstream product

• 2107-69-9 5,6-dimethoxy-1-indanone 
• 5798-76-5 phenyl 4-bromobenzoate 
• 82892-00-0 N-(4-bromobenzoyl)imidazole 
• 1204607-46-4 C₁₈H₁₄Br₂O₃ 
• 586-76-5 4-Bromobenzoic acid 

Downstream Products

• 760990-50-9 C₁₈H₁₅BrN₂O₂ 
• 760990-50-9 3-(4-bromophenyl)-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazole 

Relevant articles and documents

Design, synthesis and evaluation of novel 5,6-dimethoxy-1-oxo-2,3-dihydro-1H-2-indenyl-3,4-substituted phenyl methanone analogues

In present investigation, a series of substituted phenyl-5,6-dimethoxy-1-oxo-2,3-dihydro-1H-2-indenylmethanone analogues were synthesized and were tested for their potential for treating AD disease. All the newly synthesized compounds were showing moderate to high AChE inhibitory activities, with compound 5,6-dimethoxy-1-oxo-2,3-dihydro-1H-2-indenyl-3,4,5-trimethoxyphenylmethanone (5f) produced significant activities with 2.7 ± 0.01 μmol/L.

Synthesis and biological evaluation of 4′-(6,7-disubstituted-2,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-biphenyl-4-ol as potent Chk1 inhibitors

A new series of potent tricyclic pyrazole-based Chk1 inhibitors are described. Analogues disubstituted on the 6- and 7-positions show improved Chk1 inhibition potency compared with analogues with a single substituent on either the 6- or 7-position. Based