760995-17-3Relevant academic research and scientific papers
Synthesis and biological evaluation of 4′-(6,7-disubstituted-2,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-biphenyl-4-ol as potent Chk1 inhibitors
Tao, Zhi-Fu,Li, Gaoquan,Tong, Yunsong,Chen, Zehan,Merta, Philip,Kovar, Peter,Zhang, Haiying,Rosenberg, Saul H.,Sham, Hing L.,Sowin, Thomas J.,Lin, Nan-Horng
, p. 4308 - 4315 (2008/02/09)
A new series of potent tricyclic pyrazole-based Chk1 inhibitors are described. Analogues disubstituted on the 6- and 7-positions show improved Chk1 inhibition potency compared with analogues with a single substituent on either the 6- or 7-position. Based
