76132-33-7Relevant academic research and scientific papers
10-Aryl-7,7-dimethyl-5,6,7,8,9,10-hexahydro-11H-pyrido[3,2-b][1,4] benzodiazepin-9-ones
Tonkikh,Strakovs,Petrova
, p. 944 - 948 (2004)
In reactions of 3-(2-amino-3-pyridyl)amino-5,5-dimethylcyclohex-2-en-1-one with aromatic aldehydes (2- and 4-hydroxy-, 2-hydroxy-3-methoxy-, 4-dimethylamino-, 4-methoxy-, 2,4- and 3,4-dimethoxy-, 3,4-methylenedioxy-, 4-bromo-, 4-fluoro-, 4-chloro-, 2-nitr
1,5-Benzodiazepine inhibitors of HCV NS5B polymerase
McGowan, David,Nyanguile, Origene,Cummings, Maxwell D.,Vendeville, Sandrine,Vandyck, Koen,Van den Broeck, Walter,Boutton, Carlo W.,De Bondt, Hendrik,Quirynen, Ludo,Amssoms, Katie,Bonfanti, Jean-Francois,Last, Stefaan,Rombauts, Klara,Tahri, Abdellah,Hu, Lili,Delouvroy, Frederic,Vermeiren, Katrien,Vandercruyssen, Genevieve,Van der Helm, Liesbet,Cleiren, Erna,Mostmans, Wendy,Lory, Pedro,Pille, Geert,Van Emelen, Kristof,Fanning, Gregory,Pauwels, Frederik,Lin, Tse-I,Simmen, Kenneth,Raboisson, Pierre
scheme or table, p. 2492 - 2496 (2009/12/07)
Optimization through parallel synthesis of a novel series of hepatitis C virus (HCV) NS5B polymerase inhibitors led to the identification of (R)-11-(4-benzyloxy-2-fluorophenyl)-6-hydroxy-3,3-dimethyl-10-(6-methylpyridine-2-carbonyl)-2,3,4,5,10,11-hexahydr
