76144-20-2Relevant academic research and scientific papers
AN ENANTIOSELECTIVE ROUTE TO AN INTERMEDIATE OF THE CARBAPENAM SYSTEM FROM THE CHIRAL γ-BUTYROLACTONE
Takano, Seiichi,Kasahara, Chiyoshi,Ogasawara, Kunio
, p. 631 - 634 (2007/10/02)
A new enantioselective synthesis of the keto ester(16) containing β-lactam ring system has been developed using the chiral lactone(1) as a starting material.
SYNTHETIC STUDIES ON OPTICALLY ACTIVE β-LACTAMS. CHIRAL SYNTHESIS OF CARBAPENAM RING SYSTEM STARTING FROM L-ASPARTIC ACID
Ikota, Nobuo,Shibata, Hisanari,Koga, Kenji
, p. 1077 - 1080 (2007/10/02)
Benzyl (3R,5R)-1-carba-2-oxopenam-3-carboxylate (12), a useful synthon for β-lactams having carbapenem ring system, was synthesized in optically pure state starting from L-aspartic acid.
