76144-20-2

Basic information

• Product Name: (4R)-4-<3-(Benzyloxycarbonyl)-2-oxopropyl>azetidin-2-one
• Synonyms: (4R)-4-<3-(Benzyloxycarbonyl)-2-oxopropyl>azetidin-2-one
• CAS NO: 76144-20-2
• Molecular Weight: 261.277
• Mol File: 76144-20-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (4R)-4-<3-(Benzyloxycarbonyl)-2-oxopropyl>azetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R)-4-<3-(Benzyloxycarbonyl)-2-oxopropyl>azetidin-2-one(76144-20-2)
• EPA Substance Registry System: (4R)-4-<3-(Benzyloxycarbonyl)-2-oxopropyl>azetidin-2-one(76144-20-2)

Safety Data

• Hazardous Substances Data: 76144-20-2(Hazardous Substances Data)

Upstream product

• 103841-62-9 (R)-3-Benzylamino-4-chlorocarbonyl-butyric acid methyl ester; hydrochloride 
• 76144-15-5 1-benzyl 5-methyl (R)-3-tert-butoxycarbonylaminoglutarate 
• 80974-44-3 (S)-N-benzyl-4-carboxymethyl-2-azetidinone 
• 103841-69-6 (R)-N-benzyl-4-cyanomethyl-2-azetidinone 
• 82448-91-7 (R)-3-(2,2,2-Trichloro-ethoxycarbonylamino)-hex-5-enoic acid 
• 82448-90-6 [(R)-1-(2-Oxo-ethyl)-but-3-enyl]-carbamic acid 2,2,2-trichloro-ethyl ester 
• 82468-78-8 [(R)-1-(tert-Butyl-dimethyl-silanyl)-4-oxo-azetidin-2-yl]-acetaldehyde 
• 76144-22-4 (R)-3-Amino-pentanedioic acid benzyl ester methyl ester 
• 76144-19-9 (S)-4-carboxymethyl-2-azetidinone 
• 76144-17-7 (4R) N-Benzyl-4-methoxycarbonylmethyl-azetidin-2-one 
• 76144-16-6 5-methyl 1-hydrogen (S)-3-benzylaminoglutarate 
• 85657-44-9 (R)-4-((S)-2,4-Bis-benzyloxy-butyl)-1-(tert-butyl-dimethyl-silanyl)-azetidin-2-one 
• 85657-42-7 (R)-4-((2S,3R)-2,4-Bis-benzyloxy-3-hydroxy-butyl)-azetidin-2-one 
• 80528-12-7 benzyl 4-[(2R)-1-(tert-butyl-dimethylsilyl)-4-oxoazetidin-2-yl)but-2-enoate 

Downstream Products

• 76189-53-2 benzyl (3R,5R)-1-carba-2-oxopenam-3-carboxylate 
• 76144-21-3 (R)-4-3'-benzyloxycarbonyl-3'-diazo-2'-oxopropyl-2-azetidinone 

Relevant articles and documents

β-lactams. 1. Highly diastereoselective alkylation of 4-acetoxyazetidin-2-one useful for 1β-methylcarbapenem synthesis

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Synthesis of the precursor of (+)-thienamycin utilizing D-glucosamine

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SYNTHETIC STUDIES ON OPTICALLY ACTIVE β-LACTAMS. CHIRAL SYNTHESIS OF CARBAPENAM RING SYSTEM STARTING FROM L-ASPARTIC ACID

Benzyl (3R,5R)-1-carba-2-oxopenam-3-carboxylate (12), a useful synthon for β-lactams having carbapenem ring system, was synthesized in optically pure state starting from L-aspartic acid.