761449-05-2Relevant articles and documents
Novel oxidation of Cyclosporin A: Preparation of Cyclosporin methyl vinyl ketone (Cs-MVK)
Yang, Zhicai,Pattamana, Kevin,Molino, Bruce F.,Haydar, Simon N.,Cao, Yeyu,Bois, Frederic,Maeng, Jun-Ho,Hemenway, Michael S.,Rich, Joseph O.,Khmelnitsky, Yuri L.,Friedrich, Thomas D.,Peace, Denise,Michels, Peter C.
, p. 2935 - 2938 (2009)
Cyclosporin A (CsA) was converted into cyclosporin methyl vinyl ketone (Cs-MVK) by either a biocatalytic method utilizing 1-hydroxybenzotriazole- mediated laccase oxidation or by a chemical oxidation using t-butyl hydroperoxide and potassium -periodate as