761459-40-9Relevant academic research and scientific papers
Preparation method of (4-isopropoxy-2-methyl)phenyl isopropyl ketone
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Paragraph 0064, (2020/08/27)
The invention relates to a preparation method of (4-isopropoxy-2-methyl)phenyl isopropyl ketone. The preparation method specifically comprises the following steps: reacting m-cresol with thiocyanate under the action of a catalyst to obtain a product A; reacting the product A with halogenated isopropane under the action of an alkali and a catalyst to obtain a product B; carrying out a reaction on the product B and isopropyl magnesium halide, and carrying out a treatment to obtain the (4-isopropoxy-2-methyl)phenyl isopropyl ketone. The purity of prepared (4-isopropoxy-2-methyl)phenyl isopropyl ketone is 99% or above, and the total yield is 79% or above. According to the method, the use of toxic reagents and generation of a large amount of acid wastewater are avoided, the reaction temperatureis reduced, the reaction yield is increased, the process route is simple and efficient, the cost is reduced, the purity of the obtained product is high, the production safety is greatly improved, andindustrial popularization is facilitated.
FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE
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Page/Page column 96-97, (2008/06/13)
Conventional many fungicidal compositions have had practical problems such that either a preventive effect or a curing effect is inadequate, the residual effect tends to be inadequate, or the controlling effect against plant diseases tends to be inadequat
Improvement of Selectivity in the Fries Rearrangement and Direct Acylation Reactions by Means of P2O5/SiO2 Under Microwave Irradiation in Solvent-Free Media
Eshghi, Hossein,Rafie, Mohammad,Gordi, Zinat,Bohloli, Moosa
, p. 1258 - 1270 (2007/10/03)
P2O5/SiO2 was found to be an efficient new reagent for the Fries rearrangement of acyloxy benzene or naphthalene derivatives and the direct acylation reactions of phenol and naphthol derivatives with carboxylic acids. The reactions proceeded smoothly in the solid state and are highly selective methods for the preparation of the ortho isomers of hydroxyaryl ketones. Microwave irradiation improved the conversion yield to 85-100 percent and the high ortho-regioselectivity of these reactions provides an efficient and versatile procedure for obtaining o-hydroxyaryl ketones in 47-98 percent yield.
