76160-35-5

Usage

Molecular Structure

2-(2-IODOBENZOYL)PYRIDINE consists of a pyridine ring with a 2-iodobenzoyl group attached to it.

Usage

It is commonly used as a building block in organic synthesis and can be utilized in the construction of various molecular structures.

Application in Research

2-(2-IODOBENZOYL)PYRIDINE is often employed in medicinal and pharmaceutical research, particularly in the development of new drugs and potential treatments.

Property Modification

It is known for its ability to modify the properties and functions of other organic molecules, making it a valuable tool in the field of chemistry and drug discovery.

Antimicrobial and Anti-cancer Properties

IBP has been studied for its potential antimicrobial and anticancer properties, showing promise as a versatile and important chemical with a wide range of potential applications.

InChI:InChI=1/C12H8INO/c13-10-6-2-1-5-9(10)12(15)11-7-3-4-8-14-11/h1-8H

Upstream product

• 17624-36-1 2-pyridyllithium 
• 26260-02-6 2-iodobenzaldehyde 
• 42471-56-7 2-(2-aminobenzoyl)pyridine 
• 109-04-6 2-bromo-pyridine 
• 1885-29-6 anthranilic acid nitrile 

Downstream Products

• 1648743-78-5 (R)-2-((2-diacetoxyiodophenyl)(methoxy)methyl)pyridine 
• 1648743-79-6 (R)-(2-iodophenyl)(pyridine-2-yl)methanol 
• 5583-33-5 (R)-(-)-α-phenyl-2-pyridylmethanol 
• 1648743-80-9 (R)-2-((2-iodophenyl)(methoxy)methyl)pyridine 
• 74309-57-2 2-[1-(2-Iodo-phenyl)-vinyl]-pyridine 

Relevant academic research and scientific papers

Enantioselective diamination with novel chiral hypervalent iodine catalysts

Vicinal diamines constitute one the most important functional motif in organic chemistry because of its wide occurrence in a variety of biological and pharmaceutical molecules. We report an efficient metal-free, highly stereoselective intramolecular diamination using a novel chiral hypervalent iodine reagent together with its application as an efficient catalyst for the synthesis of diamines.

Kinetic Energy Release and Position of Transition State During the Intramolecular Substitution of Ionized 2-Benzoyl Pyridines

The loss of substituents X from molecular ions of ortho substituted 2-benzoyl pyridines has been investigated as a function of the dissociation energy of the C-X bond.Comparison of unimolecular and collisional induced decompositions of the resulting + ions and reference ions arising from 3-hydroxypyridoindole shows that cyclic fragment ions are formed in every case by an intramolecular substitution reaction with the exception of the parent compound (X=H), which gives rise to a mixture of + ions with different structures.The heat of formation of the cyclic ion has been estimated experimentally and by calculation using thermochemical data, and from this value and the appearance energies, the activation energies of the reverse reactions have been evaluated for the different reaction systems.Measurement of the kinetic energy release during the substitution reactions shows that only part of the reverse activation energy is released as kinetic energy.The energy partitioning quotient varies from 0.37 to 0.08 depending on the dissociation energy of the C-X bond or the reaction enthalpy.A sudden change in the energy partitioning quotient is observed with increasing exothermicity of the reaction, paralleling the behaviour of similar reaction systems.These results are interpreted as a demonstration of the influence of the variation of transition state position on the energy partitioning quotient.