76175-78-5Relevant articles and documents
Substances with antiviral activity. XV. Preparation and antiherpes activity of alkyl- and acylamino-dihalogenated pyrimidines and pyridines
Giovanninetti,Garuti,Cavrini,Roveri,Mannini Palenzona,Sinibaldi,Fusco
, p. 879 - 886 (2007/10/02)
Some dihalo-amino-pyrimidines and -pyridines were alkylated and acylated at the amino group. The resulting twenty-four compounds were then tested for their action on Herpes simplex virus infection in human HEp-2 cell cultures. Five compounds were active and 2-benzamido-3,5-dichloropyridine [(III B); Table I] showed the highest antiviral activity.