76184-51-5Relevant academic research and scientific papers
Interrogating Pd(II) Anion Metathesis Using a Bifunctional Chemical Probe: A Transmetalation Switch
Molloy, John J.,Seath, Ciaran P.,West, Matthew J.,McLaughlin, Calum,Fazakerley, Neal J.,Kennedy, Alan R.,Nelson, David J.,Watson, Allan J. B.
, p. 126 - 130 (2018)
Ligand metathesis of Pd(II) complexes is mechanistically essential for cross-coupling. We present a study of halide→OH anion metathesis of (Ar)PdII complexes using vinylBPin as a bifunctional chemical probe with Pd(II)-dependent cross-coupling pathways. We identify the variables that profoundly impact this event and allow control to be leveraged. This then allows control of cross-coupling pathways via promotion or inhibition of organoboron transmetalation, leading to either Suzuki-Miyaura or Mizoroki-Heck products. We show how this transmetalation switch can be used to synthetic gain in a cascade cross-coupling/Diels-Alder reaction, delivering borylated or non-borylated carbocycles, including steroid-like scaffolds.
PREPARATION AND DIELS-ALDER REACTIONS OF SOME FUNCTIONALIZED ISOPRENES
Mandai, Tadakatsu,Yokoyama, Haruyuki,Miki, Toshio,Fukuda, Haruo,Kobata, Hiroshi,et al.
, p. 1057 - 1060 (2007/10/02)
A convenient synthetic method for some functionalized isoprenes employing 1-bromo-2-phenylthioethane and ethyl acetoacetate as starting materials is reported.It has also been found that the dienes thus obtained gave functionalized limonene analogs by Diel
