22196-19-6

Upstream product

• 119-26-6 (2,4-dinitro-phenyl)-hydrazine 
• 76184-80-0 C₁₆H₂₂O₅ 
• 76184-78-6 (7S,12S)-8,12-Dimethyl-1,4-dioxa-dispiro[4.1.5.2]tetradec-8-ene 
• 32763-43-2 C₁₄H₂₀O₃ 
• 32763-43-2 C₁₄H₂₀O₃ 
• 76184-85-5 (2R,5S,10S)-6,10-Dimethyl-8-oxo-spiro[4.5]deca-3,6-diene-2-carboxylic acid methyl ester 
• 28939-31-3 (7S,12S)-8,12-Dimethyl-1,4-dioxa-dispiro[4.1.5.2]tetradec-8-en-10-one 
• 76184-77-5 Acetic acid (7S,12S)-8,12-dimethyl-1,4-dioxa-dispiro[4.1.5.2]tetradec-8-en-10-yl ester 
• 76184-66-2 3-(2,6-Dimethyl-4-oxo-cyclohex-2-enyl)-propionic acid 
• 18444-84-3 6,10t-Dimethyl-(5r-C¹)-spiro<4,5>dec-6-en-2-on 
• 76184-78-6 (7S,12R)-8,12-Dimethyl-1,4-dioxa-dispiro[4.1.5.2]tetradec-8-ene 
• 76184-77-5 Acetic acid (7S,12R)-8,12-dimethyl-1,4-dioxa-dispiro[4.1.5.2]tetradec-8-en-10-yl ester 
• 76184-72-0 rel-(5R,10S)-6,10-dimethylspiro<4.5>dec-6-ene-2,8-dione 
• 76184-74-2 rel-(5R,10S)-6,10-dimethylspiro<4.5>dec-6-ene-2,8-dione 2-ethylene acetal 

Relevant academic research and scientific papers

The total synthesis of (+/-)hinesol and (+/-)epihinesol

The tricyclic ketal ketones 15a and 15b have been obtained in an isomeric ratio of 9:1 (4 5 6 7 8 9 10 11 12 13 14 15a + 15b).Compound 15a was converted in seven (or eight) steps to (+/-)epihinesol (3) 29 32 48 49 47 (or 32 39 38 44 47) 50 3> and compound 38 was transformed into (+/-)hinesol (2) in five steps (38 76 77 62 63 2).The identity of epihinesol and agarospirol was confirmed by formation of a common epoxide.