76209-05-7Relevant academic research and scientific papers
A benzothiazole derivative and its preparation method (by machine translation)
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Paragraph 0029-0032; 0042; 0053; 0064; 0075; 0086; 0096, (2017/07/19)
The present invention provides a benzothiazole derivative and its preparation method, said styrene and thiazole derivatives of the formula the formula (I), wherein: R1 Is hydrogen, alkyl or alkoxy; R2 Is hydrogen or a halogen atom. T
Fused bicyclic-substituted amines as histamine-3 receptor ligands
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Page 18-19, (2010/02/09)
Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands and methods for using such compounds and compositions.
Fused bicyclic-substituted amines as histamine-3 receptor ligands
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Page 19-20, (2010/02/09)
Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands and methods for using such compounds and compositions.
Synthesis of 5- and 6-Substituted 2-Methylbenzothiazoles under Conditions of Metal Complex Catalysis
Bumagin,Nikitina,Beletskaya
, p. 1803 - 1811 (2007/10/03)
Methods are proposed for preparation of 5- and 6-substituted 2-methylbenzothiazoles by reactions of organozinc and organotin compounds with 5- and 6-bromo-2-methylbenzothiazoles, catalyzed by palladium complexes. The reactions of organozinc compounds with 5(6)-bromo-2-methylbenzothiazoles occur in THF at 20°C in the presence of PdCl2(dppf), and those of organotin compounds are carried out in DMF, aqueous DMF, or water at 40-100°C in the presence of PdCl2, Pd(OAc)2, or PdCl2(PPh3)2.
THE SYNTHESIS OF o-NITROBENZENETHIOLS: AN ADVANTAGEOUS NUCLEOPHILIC DISPLACEMENT ON o-CHLORONITROBENZENES
Battistoni, Paolo,Bruni, Paolo,Fava, Gabriele
, p. 301 - 304 (2007/10/02)
Reaction of substituted o-chloronitrobenzenes with sodium sulphide in DMSO occurs rapidly and gives the corresponding o-nitrobenzenethiols, following a convenient one-step pathway.Better yields are obtained when stoicheiometric amounts of sulphur, dissolved in a little carbon disulphide, are added in the presence of ethyl methyl ketone as solvent.
