76216-53-0Relevant articles and documents
Electroreductive Nickel-Catalyzed Thiolation: Efficient Cross-Electrophile Coupling for C?S Formation
Ang, Nate W. J.,Ackermann, Lutz
supporting information, p. 4883 - 4887 (2021/02/26)
Sulfur-containing molecules are of utmost topical importance towards the effective development of pharmaceuticals and functional materials. Herein, we present an efficient and mild electrochemical thiolation by cross-electrophile coupling of alkyl bromide
Indium-Catalyzed Reductive Sulfidation of Esters by Using Thiols: An Approach to the Diverse Synthesis of Sulfides
Miyazaki, Takahiro,Kasai, Shinsei,Ogiwara, Yohei,Sakai, Norio
, p. 1043 - 1049 (2016/03/01)
A new reductive preparation of unsymmetrical sulfides from esters and thiols in the presence of InI3 and either 1,1,3,3-tetramethyldisiloxane (TMDS) or PhSiH3 as the reductant was developed. This protocol was applied to not only benzoic acid esters that have a methoxy, methyl, chloro, bromo, iodo, or trifluoromethyl group on the aromatic ring but also aliphatic acid esters with either aromatic or aliphatic thiols. A reaction mechanism is proposed by using Hammett plot results and several control experiments. The reductive preparation of unsymmetrical sulfides from esters and thiols by using InI3 and either 1,1,3,3-tetramethyldisiloxane (TMDS) or PhSiH3 was developed. Several mechanistic studies support that the present transformation proceeds through O,S-and S,S-acetals as the reaction intermediates. TMDS = 1,1,3,3-tetramethyldisiloxane, R = aliphatic group.
Alkylthioether synthesis via imidazole mediated Mitsunobu condensation
Falck,Lai, Jing-Yu,Cho, Su-Dong,Yu, Jurong
, p. 2903 - 2906 (2007/10/03)
Unsymmetric alkylthioethers can be prepared from aliphatic thiols and unhindered alcohols under modified Mitsunobu conditions using trimethylphosphine/1,1'-(azodicarbonyl)dipiperdine (ADDP) in the presence of imidazote (2 equivalents).
