76217-30-6

Upstream product

• 19722-31-7 4-hydrazino-1H-2,3-benzoxazine 
• 591-31-1 3-methoxy-benzaldehyde 

Downstream Products

• 75318-77-3 5-(2-hydroxymethylphenyl)-3-(3-methoxyphenyl)-1H,-1,2,4-triazole 
• 76217-33-9 2-<3-(3-methoxyphenyl)-s-triazol-5-yl>benzaldehyde 
• 75318-77-3 3-<2-(hydroxymethyl)phenyl>-5-(3-methoxyphenyl)-s-triazole 

Relevant academic research and scientific papers

A New Class of Nonhormonal Pregnancy-Terminating Agents. Synthesis and Contragestational Activity of 3,5-Diaryl-s-triazoles

A series of 3,5-diaryl-s-triazoles were synthesized and evaluated as postimplantation contragestational agents.The introduction of various substituents (e.g., an o-alkyl chain on one phenyl and a m-alkoxy group on the other) was found to increase the potency.Several compounds with very high pregnancy-terminating activity in both hamsters and rats were obtained.One of these, 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-s-triazole, DL 111 (36), was selected for detailed evaluation in various animal species.A synthetic scheme for the preparation of these compounds and preliminary structure-activity relationships are presented.