762173-00-2Relevant academic research and scientific papers
Synthesis and SAR studies of very potent imidazopyridine antiprotozoal agents
Biftu, Tesfaye,Feng, Dennis,Fisher, Michael,Liang, Gui-Bai,Qian, Xiaoxia,Scribner, Andrew,Dennis, Richard,Lee, Shuliang,Liberator, Paul A.,Brown, Chris,Gurnett, Anne,Leavitt, Penny S.,Thompson, Donald,Mathew, John,Misura, Andrew,Samaras, Samantha,Tamas, Tamas,Sina, Joseph F.,McNulty, Kathleen A.,McKnight, Crystal G.,Schmatz, Dennis M.,Wyvratt, Matthew
, p. 2479 - 2483 (2006)
Compounds 10a (IC50 110 pM) and 21 (IC50 40 pM) are the most potent inhibitors of Eimeria tenella cGMP-dependent protein kinase activity reported to date and are efficacious in the in vivo antiparasitic assay when administered to chi
Antiprotozoal imidazopyridine compounds
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Page/Page column 12, (2008/06/13)
Compounds described by the Formula (I) or (II): or pharmaceutically acceptable salts, or N-oxides thereof. The compounds are useful for the treatment and prevention of protozoal diseases in mammals and birds. A method for controlling coccidiosis in poultr
