Bioorganic and Medicinal Chemistry Letters p. 2479 - 2483 (2006)
Update date:2022-08-03
Topics:
Biftu, Tesfaye
Feng, Dennis
Fisher, Michael
Liang, Gui-Bai
Qian, Xiaoxia
Scribner, Andrew
Dennis, Richard
Lee, Shuliang
Liberator, Paul A.
Brown, Chris
Gurnett, Anne
Leavitt, Penny S.
Thompson, Donald
Mathew, John
Misura, Andrew
Samaras, Samantha
Tamas, Tamas
Sina, Joseph F.
McNulty, Kathleen A.
McKnight, Crystal G.
Schmatz, Dennis M.
Wyvratt, Matthew
Compounds 10a (IC50 110 pM) and 21 (IC50 40 pM) are the most potent inhibitors of Eimeria tenella cGMP-dependent protein kinase activity reported to date and are efficacious in the in vivo antiparasitic assay when administered to chi
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