7622-44-8

Upstream product

• 106129-86-6 1-(2-hydroxyphenyl)-3-dimethylaminoprop-2-enone 
• 89466-08-0 2-hydroxyphenyl boronic acid 
• 122775-34-2 3-iodo-chromen-4-one 
• 118-93-4 o-hydroxyacetophenone 

Downstream Products

• 1026236-24-7 [2-(4-Oxo-4H-chromen-3-yl)-phenoxy]-acetic acid ethyl ester 
• 111474-25-0 2'-Hydroxy-isoflavon-4-ol 
• 1026593-92-9 [2-(4-Oxo-4H-chromen-3-yl)-phenoxy]-acetyl chloride 
• 144849-58-1 [2-(4-Oxo-4H-chromen-3-yl)-phenoxy]-acetic acid 
• 125092-52-6 [2-(4-Oxo-4H-chromen-3-yl)-phenoxy]-acetic acid 2-thioxo-2H-pyridin-1-yl ester 
• 395648-85-8 C₁₇H₁₄⁽²⁾H₂O₄ 
• 395648-84-7 C₁₇H₁₅⁽²⁾HO₄ 
• 395648-83-6 C₁₇H₁₅⁽²⁾HO₄ 
• 395648-82-5 3-(2-methoxymethoxy-phenyl)-chroman-4-one 
• 395648-81-4 2'-methoxymethoxyisoflavone 

Relevant academic research and scientific papers

Development of a general approach to the synthesis of a library of isoflavonoid derivatives

Isoflavonoids are a class of organic compounds that act primarily as antioxidants. They are produced almost exclusively by various members of the bean family including soybeans, tofu, peanuts, chick peas, and alfalfa. The antioxidant characteristics that isoflavonoids exhibit help hinder the progression of certain cancers, primarily breast, prostate, and colon cancer. We have developed a three-five step synthesis for obtaining a suite of isoflavonoid derivatives. The synthesis involves an enamine formation, a ring closure and halogenation, a Suzuki coupling, and finally a global deprotection to obtain the respective isoflavonoid derivatives.