76222-40-7

Upstream product

• 505-23-7 1,3 dithiane 
• 76222-39-4 5-bromo-1-(2',3'-O-isopropylidene-5'-O-trityl-β-D-ribofuranosyl)uracil 
• 76222-41-8 (5S,6S)-5-bromo-5,6-dihydro-6-(1,3-dithian-2-yl)-2',3'-O-isopropylidene-5'-O-trityluridine 
• 76222-41-8 (5R,6S)-5-bromo-5,6-dihydro-6-(1,3-dithian-2-yl)-2',3'-O-isopropylidene-5'-O-trityluridine 
• 54503-61-6 2',3'-O-isopropylidene-5-bromouridine 
• 76-83-5 trityl chloride 

Downstream Products

• 76222-43-0 (6S)-5,6-dihydro-2',3'-O-isopropylidene-6-methyl-5'-O-trityluridine 
• 76222-47-4 C₃₃H₃₅N₅O₇ 

Relevant academic research and scientific papers

SYNTHESIS OF 6-SUBSTITUTED URIDINES. SYNTHESIS OF (R OR S)-6-(3-AMINO-2-CARBOXYPROPYL)URIDINE

Addition of 5-bromo-2',3'-O-isopropylidene-5'-O-trityluridine (2) in pyridine to an excess of 2-lithio-1,3-dithiane (3) in oxolane at -78 degC gave (6R)-5,6-dihydro-(1,3-dithian-2-yl)-2',3'-O-isopropylidene-5'-O-trityluridine (4), (5S,6S)-5-bromo-5,6-dihy