762263-72-9

Upstream product

• 37567-78-5 1,5-dimethoxy-1,4-cyclohexadiene 
• 473312-89-9 (E)-1-tert-butyldimethylsilyloxy-5-iodo-3-methylpent-2-ene 
• 213816-70-7 (E)-[(4-bromo-3-methylbut-2-en-1-yl)oxy](tert-butyl)dimethylsilane 
• 108734-49-2 (E)-4-(tert-butyldimethylsilyloxy)-1-chloro-2-methyl-2-butene 

Downstream Products

• 762263-73-0 2-[(E)-5'-tert-butyldimethylsilyloxy-3'-methyl-3'-pentenyl]-3-methoxy-2-cyclohexen-1-one 
• 762263-77-4 (S)-2-Methoxy-2-naphthalen-1-yl-propionic acid (1S,4S)-4-[(2E,6Z)-7-(tert-butyl-dimethyl-silanyloxymethyl)-3,11-dimethyl-dodeca-2,6,10-trienyl]-2-[(E)-5-(tert-butyl-dimethyl-silanyloxy)-3-methyl-pent-3-enyl]-3-methyl-cyclohex-2-enyl ester 
• 762263-74-1 2-[(E)-5'-tert-butyldimethylsilyloxy-3'-methyl-3'-pentenyl]-6-[(2''E,6''Z)-7''-tert-butyldiphenylsilyloxymethyl-3'',11''-dimethyl-2'',6'',10''-dodecatrienyl]-3-methoxy-2-cyclohexen-1-one 
• 762263-76-3 (2S,1'S,4'S)-2-[(E)-5''-hydroxy-3''-methyl-3''-pentenyl]-4-[(2'''E,6'''Z)-7'''-hydroxymethyl-3''',11'''-dimethyl-2''',6''',10'''-dodecatrienyl]-3-methyl-2-cyclohexen-1-yl 2-methoxy-2-(1-naphthyl)propionate 
• 762263-84-3 (2S,1'R,4'R)-2-[(E)-5''-hydroxy-3''-methyl-3''-pentenyl]-4-[(2'''E,6'''Z)-7'''-hydroxymethyl-3''',11'''-dimethyl-2''',6''',10'''-dodecatrienyl]-3-methyl-2-cyclohexen-1-yl 2-methoxy-2-(1-naphthyl)propionate 
• 762263-85-4 (1R,4R)-2-[(E)-5'-tert-butyldimethylsilyloxy-3'-methyl-3'-pentenyl]-4-[(2''E,6''Z)-7''-tert-butyldimethylsilyloxymethyl-3'',11''-dimethyl-2'',6'',10''-dodecatrienyl]-3-methyl-2-cyclohexen-1-ol 
• 762263-78-5 (1S,4S)-2-[(E)-5'-tert-butyldimethylsilyloxy-3'-methyl-3'-pentenyl]-4-[(2''E,6''Z)-7''-tert-butyldimethylsilyloxymethyl-3'',11''-dimethyl-2'',6'',10''-dodecatrienyl]-3-methyl-2-cyclohexen-1-ol 
• 473312-93-5 2-[(E)-5'-tert-butyldimethylsilyloxy-3'-methyl-3'-pentenyl]-4-[(2''E,6''Z)-7''-tert-butyldiphenylsilyloxymethyl-3'',11''-dimethyl-2'',6'',10''-dodecatrienyl]-3-methyl-2-cyclohexen-1-one 

Relevant academic research and scientific papers

Synthesis of (±)-mispyric acid, a triterpene inhibitor of DNA polymerase β isolated from Mischocarpus pyriformis

The first synthesis of (±)-mispyric acid, an inhibitor of DNA polymerase β with a novel triterpene skeleton, was achieved by starting from isoprene, geraniol and 1,5-dimethoxy-1,4-cyclohexadiene.

Triterpenoid total synthesis. Synthesis and absolute configuration of mispyric acid

The first synthesis of mispyric acid (1), an inhibitor β DNA polymerase β with a novel triterpene skeleton, was achieved by starting from isoprene (2), geraniol (6) and 1,5-dimethoxy-1,4-cyclohexadiene (14). The absolute configuration of the naturally occ