76227-24-2

Upstream product

• 76227-21-9 N'-benzyloxy-1-(2-deoxy-β-D-ribofuranosyl)-5-formamido-1H-imidazole-4-carboxamidine 
• 3506-01-2 2'-Deoxyadenosine N¹-oxide 
• 76227-21-9 N'-benzyloxy-1-(2-deoxy-β-D-ribofuranosyl)-5-formamidoimidazole-4-carboxamidine 
• 104-15-4 toluene-4-sulfonic acid 
• 76227-22-0 N-Benzyloxy-5-(formyl-methyl-amino)-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-imidazole-4-carboxamidine 
• 76227-22-0 N'-benzyloxy-1-(2-deoxy-β-D-ribofuranosyl)-5-(N-methylformamido)-1H-imidazole-4-carboxamidine 

Downstream Products

• 5142-23-4 3-methyladenine 
• 76227-26-4 3-methyl-2'-deoxyadenosine hydrotoluene-4-sulfonate 

Relevant academic research and scientific papers

Synthesis, Ring Opening, and Glycosidic Bond Cleavage of 3-Methyl-2'-deoxyadenosine

Methylation of N'-benzyloxy-1-(2-deoxy-β-D-ribofuranosyl)-5-formamidoimidazole-4-carboxamidine (2a) followed by hydrogenolysis of the N'-benzyloxy-group and cyclization produced the hitherto unknown 3-methyl-2'-deoxyadenosine (5a), which was readily hydrolysed to 3-methyladenine (6) in H2O at pH /=7.0 and to (6) and the imidazole-(2-deoxy)riboside (4a) at pH 8.98.