762275-96-7Relevant academic research and scientific papers
Substituted 6-phenyl-pyridin-2-ylamines: Selective and potent inhibitors of neuronal nitric oxide synthase
Nason, Deane M.,Heck, Steven D.,Bodenstein, Mathew S.,Lowe III, John A.,Nelson, Robert B.,Liston, Dane R.,Nolan, Charles E.,Lanyon, Lorraine F.,Ward, Karen M.,Volkmann, Robert A.
, p. 4511 - 4514 (2007/10/03)
The synthesis and nNOS and eNOS activity of 6-(4-(dimethylaminoalkyl)-/6- (4-(dimethylaminoalkoxy)-5-ethyl-2-methoxyphenyl)-pyridin-2-ylamines and 6-(4-(dimethylaminoalkyl)-/6-(4-(dimethylaminoalkoxy)-2,5-dimethoxyphenyl) -pyridin-2-ylamines 1-8 are described. These compounds are potent inhibitors of the human nNOS isoform.
2-AMINO-6-(2-SUBSTITUTED-4-PHENOXY)-SUBSTITUTED-PYRIDINES
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, (2008/06/13)
This present invention relates to compounds of the formula wherein G, R1 and R2 are defined as in the specification, to pharmaceutical compositions containing them and to their use in the treatment and prevention of central nervous system and other disorders.
