7626-84-8Relevant academic research and scientific papers
Metal-Free Direct C–H Thiolation and Thiocyanation of Pyrazolones
Kittikool, Tanakorn,Yotphan, Sirilata
, (2020)
Metal-free approach for direct C–H thiolation and thiocyanation of N-substituted pyrazolones with disulfides and thiocyanate salts, respectively, are developed. These reactions allow the C–S bond coupling to proceed effectively under mild conditions, providing useful and convenient methods for preparation of a series of 4-thio-substituted pyrazolone analogues, which have potential applications in organic, medicinal and material chemistry. Preliminary mechanistic investigation suggested that radical processes are likely to involve in these transformations.
