76260-78-1

Basic information

• Product Name: ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OME
• Synonyms: methylester-substance;SUBSTANCE P METHYL ESTER;ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OME;H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OME;[MET-OME11]-SUBSTANCE P;Substance P, [Met-OMet11];Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-OMe, Substance P methyl ester;L-Arg-L-Pro-L-Lys-L-Pro-Gln-L-Gln-L-Phe-L-Phe-Gly-L-Leu-L-Met-OMe
• CAS NO: 76260-78-1
• Molecular Formula: C₆₄H₉₉N₁₇O₁₄S
• Molecular Weight: 1362.64
• Mol File: 76260-78-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.41g/cm³
• Refractive Index: 1.653
• Storage Temp.: −20°C
• CAS DataBase Reference: ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OME(CAS DataBase Reference)
• NIST Chemistry Reference: ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OME(76260-78-1)
• EPA Substance Registry System: ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OME(76260-78-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 76260-78-1(Hazardous Substances Data)

Usage

General Description

The chemical compound "ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OME" is a peptide composed of amino acids arranged in a specific sequence. It begins with the amino acids arginine (ARG), proline (PRO), lysine (LYS) and proline (PRO) followed by glutamine (GLN) repeated twice, then phenylalanine (PHE) also repeated twice, and ending with glycine (GLY), leucine (LEU) and methionine (MET) with an O-methyl (OME) group attached. This chemical compound is likely to have biological significance as peptides play crucial roles in various biological processes such as signal transduction, enzyme regulation, and cell communication.

InChI:InChI=1/C63H97N17O14S/c1-37(2)33-45(56(87)76-44(27-32-95-4)62(93)94-3)72-52(83)36-71-53(84)46(34-38-15-7-5-8-16-38)77-57(88)47(35-39-17-9-6-10-18-39)78-55(86)41(22-24-50(66)81)73-54(85)42(23-25-51(67)82)74-58(89)49-21-14-31-80(49)61(92)43(19-11-12-28-64)75-59(90)48-20-13-30-79(48)60(91)40(65)26-29-70-63(68)69/h5-10,15-18,37,40-49H,11-14,19-36,64-65H2,1-4H3,(H2,66,81)(H2,67,82)(H,71,84)(H,72,83)(H,73,85)(H,74,89)(H,75,90)(H,76,87)(H,77,88)(H,78,86)(H4,68,69,70)/t40-,41-,42-,43-,44-,45-,46-,47-,48-,49-/m0/s1

Upstream product

• 4530-20-5 BOC-glycine 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 2488-15-5 N-tert-butoxycarbonyl-L-methionine 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 101914-73-2 (N^α-Z-Arg¹,N^ε-Z-Lys³)-SP-OMe 

Relevant articles and documents

Analogues of Substance P. Peptides containing D-amino acid residues in various positions of substance P and displaying agonist or receptor selective antagonist effects

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