76282-67-2Relevant academic research and scientific papers
Pteridines. 48. Utilization of 3,3-Dimethoxy-2-pyrrolidinopropene for the Synthesis of Folic Acid, N2'-Acetyl-7-folic Acid, and 5-Deaza-7-folic Acid
Taylor, Edward C.,Dumas, Donald J.
, p. 1394 - 1402 (2007/10/02)
3,3-Dimethoxy-2-pyrrolidinopropene (7) is shown to be a useful intermediate for the synthesis of 6-formylpterin (1), 7-formylpterin (8), and 5-deaza-7-formylpterin (9).Thus, treatment of 7 with nitrosyl chloride followed by hydrolysis gives 1,1-dimethoxy-
