763-11-1

Basic information

• Product Name: N,N'-dibutylsulphamide
• Synonyms: N,N'-dibutylsulphamide;N,N'-Dibutylsulfamide
• CAS NO: 763-11-1
• Molecular Formula: C₈H₂₀N₂O₂S
• Molecular Weight: 208.3216
• EINECS: 212-107-1
• Mol File: 763-11-1.mol
• Article Data: 7

Chemical Properties

• Melting Point: 38-39 °C
• Boiling Point: 295.0±23.0 °C(Predicted)
• Appearance: /
• Density: 1.045±0.06 g/cm3(Predicted)
• PKA: 11.82±0.40(Predicted)
• CAS DataBase Reference: N,N'-dibutylsulphamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-dibutylsulphamide(763-11-1)
• EPA Substance Registry System: N,N'-dibutylsulphamide(763-11-1)

Safety Data

• Hazardous Substances Data: 763-11-1(Hazardous Substances Data)

Upstream product

• 10305-43-8 butylsulfamoyl chloride 
• 109-73-9 N-butylamine 

Downstream Products

• 3488-39-9 N-n-Butyl-N'-cyclohexylsulfamide 
• 1744-71-4 N,N′-dibutylhydrazine 

Relevant articles and documents

The Zeolite ZSM-5-SO3H as an Effcient Mild Heterogeneous Catalyst for the Synthesis of 1,2,5-Thiadiazolidines, 1,2,6-Thiadiazines, and Benzo[d][1,2,7] thiadiazepines Under Microwave-assisted Solvent-free Conditions

Three series of compounds namely,1,2,5-thiadiazolidine-3,4(H)-dione-1,1-dioxydes, 1,2,6-thiadiazine-3,5(H)-dione-1,1-dioxydes, and benzo[d][1,2,7]thiadiazepine-1,5(2H)-dione-3,3-dioxydes have been synthesized by the acylation of N,N’-disubstituted symmetric sulfamides with oxalyl chloride, malonyl chloride, and phthaloyl chloride, respectively. These compounds were prepared under conventional and microwave-assisted solvent-free reaction conditions using the zeolite ZSM-5-SO3H as catalyst.

Hypervalent iodine reagent mediated diamination of [60]fullerene with sulfamides or phosphoryl diamides

A hypervalent iodine-promoted intermolecular diamination reactions of C60 with sulfamides or phosphoryl diamides affords two classes of novel C60-fused cyclic sulfamide or phosphoryl diamide derivatives. The reaction between C60 and sulfamides can be effectively controlled to selectively synthesize diamination products or azafulleroids under PhIO/I2 or PhI(OAc)2/I2 conditions, respectively. Moreover, phosphoryl diamides were first used as an amine source in the diamination of alkenes.

3D-QSAR design of novel antiepileptic sulfamides

A three-dimensional quantitative structure-activity relationship method, the comparative molecular field analysis (CoMFA), was applied to design new anticonvulsant symmetric sulfamides. The training set (27 structures) was comprised by traditional and new-generation anticonvulsant (AC) ligands that exhibit a potent activity in MES test. Physicochemical determinants of binding, such as steric and electrostatic properties, were mapped onto the molecular structures of the set, in order to interpret graphically the CoMFA results in terms of field contribution maps. The 3D-QSAR models demonstrate a good ability to predict the activity of the designed compounds (r2 = 0.967, q2 = 0.756).