763-35-9

Basic information

• Product Name: 3-MERCAPTOPROPIONAMIDE
• Synonyms: 3-MERCAPTOPROPIONAMIDE;PropanaMide, 3-Mercapto-
• CAS NO: 763-35-9
• Molecular Formula: C₃H₇NOS
• Molecular Weight: 105.16
• Mol File: 763-35-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 307.7°C at 760 mmHg
• Flash Point: 139.9°C
• Appearance: /
• Density: 1.131g/cm³
• Vapor Pressure: 0.000712mmHg at 25°C
• Refractive Index: 1.501
• CAS DataBase Reference: 3-MERCAPTOPROPIONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-MERCAPTOPROPIONAMIDE(763-35-9)
• EPA Substance Registry System: 3-MERCAPTOPROPIONAMIDE(763-35-9)

Safety Data

• Hazardous Substances Data: 763-35-9(Hazardous Substances Data)

Usage

Uses

3-Mercaptopropanamide is a useful building block, used in the synthesis of cyclic thiolactone peptide derivatives with antibiotic activity, and also in the preparation of polyclonal antibodies against brominated proteins.

InChI:InChI=1/C3H7NOS/c4-3(5)1-2-6/h6H,1-2H2,(H2,4,5)

Upstream product

• 79-06-1 2-propenamide 
• 6951-66-2 S-(2-Carbamoyl-ethyl)-isothioharnstoff 
• 33344-80-8 2-methoxyethyl mercaptopropionate 
• 1002-09-1 S-(3-amino-3-oxopropyl)ethanethioate 
• 2935-90-2 Methyl 3-mercaptopropionate 
• 1336-21-6 ammonium hydroxide 
• 1119-62-6 3,3'-dithiobis(propionic acid) 
• 1002-19-3 3,3'-disulfanediylpropanamide 

Downstream Products

• 29177-31-9 1-benzyl-3',4',5',6'-tetrahydrospiro-4'-one 
• 1436711-25-9 C₁₅H₁₅N₃OS 
• 67839-27-4 4-[4-(4-oxo-[1,3]thiazinan-2-yl)-phenoxy]-butyronitrile 
• 67839-36-5 4-(4-oxo-[1,3]thiazinan-2-yl)-benzoic acid ethyl ester 
• 67839-24-1 [4-(4-oxo-[1,3]thiazinan-2-yl)-phenoxy]-acetic acid ethyl ester 
• 67839-38-7 2-(3,5-dibromo-4-hydroxy-phenyl)-[1,3]thiazinan-4-one 
• 67839-26-3 [2,6-dibromo-4-(4-oxo-[1,3]thiazinan-2-yl)-phenoxy]-acetic acid ethyl ester 
• 1312682-13-5 C₂₇H₂₉FN₂O₃S 
• 40516-58-3 4-(chloromethyl)-2-propylthiazole 
• 180858-16-6 3-{(1R,2R)-2-Hydroxy-2-[(2S,4R)-4-(4-methoxy-benzyl)-5-oxo-tetrahydro-furan-2-yl]-1-phenyl-ethylsulfanyl}-propionamide 
• 180858-15-5 3-[(1R,2R)-2-((2S,4R)-4-Benzyl-5-oxo-tetrahydro-furan-2-yl)-2-hydroxy-1-phenyl-ethylsulfanyl]-propionamide 
• 84851-60-5 3-<(phenylpentyl)thio>propanamide 
• 67839-35-4 2-(4-dimethylamino-phenyl)-[1,3]thiazinan-4-one 
• 82697-79-8 2-(4-methoxy-phenyl)-[1,3]thiazinan-4-one 

Relevant articles and documents

A method for preparing thiol compounds

The invention provides a preparation method of a thiol compound. According to the preparation method, gas-liquid reaction is carried out on sulfuretted hydrogen and an organic compound containing carbon-carbon double bonds in a solid base catalyst and a reaction solvent through Michael addition under the conditions that the temperature is 20-80 DEG C and the pressure is 0.10-0.12MPa, so as to prepare the thiol compound. The preparation method is mild in reaction condition; the adopted solid base catalyst is strong in alkalinity; the alkaline catalysis position has relatively strong steric hindrance, and the applicability is wide; the solid base catalyst is easy to filter and recover, and can be repeatedly used after being activated; the reaction conversion rate and the selectivity are high; the side reaction is reduced; and the atomic economic utilization rate of the reaction is high.

ESTER PRODRUGS

This invention relates to ester prodrugs for alkanoic acid compounds useful as leukotriene antagonists, and pharmaceutical compositions containing such ester prodrug compounds. This invention also relates to methods of treating diseases in which leukotrienes are a factor by administration of an effective amount of the above compounds or compositions.

THIOPHENYL ALKANOIC ACIDS USEFUL AS LEUKOTRIENE ANTAGONISTS

This invention relates to alkanoic acid compounds having phenyl and thio substituents which are useful as leukotriene antagonists and pharmaceutical compositions containing such compounds. This invention also relates to treating diseases in which leukotrienes are a factor by administration of an effective amount of the above compounds or compositions.