763027-00-5

Basic information

• Product Name: (2-amino-6-(trifluoromethyl)phenyl)methanol
• Synonyms: (2-amino-6-(trifluoromethyl)phenyl)methanol
• CAS NO: 763027-00-5
• Molecular Formula: C₈H₈F₃NO
• Molecular Weight: 191.15
• Mol File: 763027-00-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2-amino-6-(trifluoromethyl)phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-amino-6-(trifluoromethyl)phenyl)methanol(763027-00-5)
• EPA Substance Registry System: (2-amino-6-(trifluoromethyl)phenyl)methanol(763027-00-5)

Safety Data

• Hazardous Substances Data: 763027-00-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(2-amino-6-(trifluoromethyl)phenyl)methanol is used as a building block for the development of new drugs and therapeutic agents due to its unique structural features and the presence of the amino group, which allows for further chemical modifications and enhancements of pharmacological properties.
Used in Agrochemical Industry:
(2-amino-6-(trifluoromethyl)phenyl)methanol is used as a key intermediate in the synthesis of agrochemicals, leveraging its stability and lipophilicity to improve the effectiveness and target specificity of these compounds in agricultural applications.
Used in Material Sciences:
(2-amino-6-(trifluoromethyl)phenyl)methanol is used as a component in the development of new materials, taking advantage of its structural properties to create materials with specific characteristics for various applications in science and engineering.

Upstream product

• 314-46-5 6-trifluoromethyl anthranilic acid 

Downstream Products

• 58579-64-9 2-Amino-6-trifluoromethylbenzyl chloride 
• 1347720-89-1 C₂₂H₂₄F₃N₃O₅ 
• 1289209-47-7 2-amino-6-(trifluoromethyl)benzaldehyde 

Relevant articles and documents

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Organic electroluminescent materials and devices are disclosed. Novel ligands for metal complex compounds that are useful as a phosphorescent emitter in organic light emitting devices that incorporate fluorinated side chains in the ligands are disclosed.

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We have reported previously the novel δ opioid agonist KNT-127 which showed high affinity and selectivity for the δ receptor. Moreover, the analgesic effect of subcutaneously administered KNT-127 was more potent than that of a prototypical δ agonist (-)-TAN-67 in the acetic acid writhing test. This study of the structure-activity relationship of KNT-127 derivatives focused on the introduction of substituents onto the 5′-, 6′-, 7′- or 8′-position of the quinoline ring and revealed that many derivatives with 5′- or 8′-substituents showed high affinities and selectivities for the δ receptor. Especially, SYK-153 with an 8′-OH group showed the highest affinity and the most balanced and highest selectivity for the δ receptor among the synthesized compounds.

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Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones

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