763033-76-7

Upstream product

• 7743-29-5 [3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propyl]-triphenyl-phosphonium bromide 
• 74591-95-0 (Z)-N-(4-(4-methylphenyl)but-3-enyl)phthalimide 

Downstream Products

• 428453-35-4 N-(4-toluenesulfonyl)-(Z)-4-(4-methylphenyl)but-3-enylamine 

Relevant academic research and scientific papers

Bronsted acid-catalyzed intramolecular hydroamination of protected alkenylamines. Synthesis of pyrrolidines and piperidines.

[reaction: see text]. The cyclization of aminoalkenes bearing an electron-withdrawing group on the nitrogen atom was catalyzed by triflic or sulfuric acid in toluene. Pyrrolidines and piperidines were formed in excellent yields. N-phenylanilides also underwent cyclization to form gamma-lactams.